RSS340613

• Gene Symbol: Akr1c3
• Gene Name: aldo-keto reductase family 1, member C3
• Gene Aliases: Akr1c18
• Chromosome Location: Chr.17: 69761126 - 69778021 on Build Rnor_6.0
• UniGene ID: Rn.10030
• Species: Rat

siRNA Details

Gene Symbol: Akr1c3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_138510.1	NP_612519.1	6	658
GenBank mRNA	BC086579.1	-	6	657
	BC100248.1	-	6	652	7307214
	D14424.1	-	6	643
	L32601.1	-	6	658

More Information

Panther Classification:

Molecular Function -

oxidoreductase, reductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

protein import into nucleus, translocation
prostaglandin metabolic process
progesterone catabolic process
G-protein coupled receptor signaling pathway
parturition
response to nutrient
steroid metabolic process
positive regulation of cell proliferation
male gonad development
cellular response to starvation
positive regulation of cell death
farnesol catabolic process
keratinocyte differentiation
cellular response to reactive oxygen species
progesterone metabolic process
retinal metabolic process
multicellular organismal macromolecule metabolic process
daunorubicin metabolic process
doxorubicin metabolic process
regulation of retinoic acid receptor signaling pathway
regulation of steroid biosynthetic process
positive regulation of protein kinase B signaling
oxidation-reduction process
testosterone biosynthetic process
cellular response to cadmium ion
cellular response to calcium ion
cellular response to prostaglandin stimulus
cellular response to corticosteroid stimulus
cellular response to jasmonic acid stimulus
cellular response to prostaglandin D stimulus
negative regulation of retinoic acid biosynthetic process
regulation of testosterone biosynthetic process
positive regulation of endothelial cell apoptotic process
positive regulation of reactive oxygen species metabolic process

Function(s)

retinal dehydrogenase activity
alditol:NADP+ 1-oxidoreductase activity
retinol dehydrogenase activity
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
phenanthrene 9,10-monooxygenase activity
dihydrotestosterone 17-beta-dehydrogenase activity
geranylgeranyl reductase activity
ketoreductase activity
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
androsterone dehydrogenase activity
ketosteroid monooxygenase activity
delta4-3-oxosteroid 5beta-reductase activity