VHS40802

Gene Symbol:

MAP2K2 LOC407835

Gene Name:

mitogen-activated protein kinase kinase 2

mitogen-activated protein kinase kinase 2 pseudogene

Gene Aliases:

CFC4, MAPKK2, MEK2, MKK2, PRKMK2

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Chromosome Location:

Chr.19: 4090321 - 4124184 on Build GRCh38

Chromosome Location:

Chr.7: 129126271 - 129128007 on Build GRCh38

UniGene ID:

Hs.465627

Hs.592273

Species:

Human

Species Specific ID (Flybase ID):

-

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siRNA Details

Gene Symbol: MAP2K2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_030662.3	NP_109587.1	2	460
	XM_006722799.2	XP_006722862.1	2	515
	XM_017026989.1	XP_016882478.1	2	515
	XM_017026990.1	XP_016882479.1	2	515
	XM_017026991.1	XP_016882480.1	2	515
GenBank mRNA	BC000471.2	-	2	460	2961198
	BC018645.2	-	2	402	4025987
	BX538081.1	-	3	210
	L11285.1	-	2	290

Gene Symbol: LOC407835
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_002144.1		1	450

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
heart development
negative regulation of gene expression
peptidyl-tyrosine phosphorylation
thyroid gland development
regulation of stress-activated MAPK cascade
proteolysis in other organism
peptidyl-serine autophosphorylation
positive regulation of transcription, DNA-templated
thymus development
regulation of axon regeneration
positive regulation of axonogenesis
face development
trachea formation
epithelial cell proliferation involved in lung morphogenesis
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
positive regulation of protein serine/threonine kinase activity
regulation of Golgi inheritance
positive regulation of production of miRNAs involved in gene silencing by miRNA
positive regulation of cell motility
regulation of early endosome to late endosome transport

Function(s)

protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
MAP kinase kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
PDZ domain binding
protein complex scaffold
protein serine/threonine kinase activator activity
metal ion binding
scaffold protein binding