n261422

• Gene Symbol: FGF1
• Gene Name: fibroblast growth factor 1
• Gene Aliases: AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1
• Chromosome Location: Chr.5: 142592178 - 142698070 on Build GRCh38
• UniGene ID: Hs.483635
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FGF1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001257205.1	NP_001244134.1	1	179
	NM_001257206.1	NP_001244135.1	1	179
GenBank mRNA	AK289762.1	-	1	119
	DC344309.1	-	1	179
	DQ655917.2	-	1	161
	M60515.1	-	1	53

More Information

Panther Classification:

Molecular Function -

growth factor, intercellular signal molecule

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
angiogenesis
organ induction
signal transduction
multicellular organism development
cell proliferation
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
anatomical structure morphogenesis
positive regulation of endothelial cell migration
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
cell differentiation
lung development
positive regulation of cell migration
activation of protein kinase B activity
cellular response to heat
phosphatidylinositol-3-phosphate biosynthetic process
positive regulation of MAP kinase activity
positive regulation of GTPase activity
positive regulation of cholesterol biosynthetic process
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
positive regulation of epithelial cell proliferation
positive regulation of cell division
branch elongation involved in ureteric bud branching
positive regulation of ERK1 and ERK2 cascade
mesonephric epithelium development
regulation of endothelial tube morphogenesis
positive regulation of intracellular signal transduction
positive regulation of sprouting angiogenesis
regulation of endothelial cell chemotaxis to fibroblast growth factor

Function(s)

protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
fibroblast growth factor receptor binding
integrin binding
protein binding
growth factor activity
heparin binding
1-phosphatidylinositol-3-kinase activity
Hsp70 protein binding
S100 protein binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity