n289091

• Gene Symbol: CFLAR
• Gene Name: CASP8 and FADD like apoptosis regulator
• Gene Aliases: CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS
• Chromosome Location: Chr.2: 201116015 - 201172688 on Build GRCh38
• UniGene ID: Hs.390736
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CFLAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001127183.2	NP_001120655.1	10	7615
	NM_001202515.1	NP_001189444.1	6	6681
	NM_001202516.1	NP_001189445.1	8	7482
	NM_001202517.1	NP_001189446.1	9	7169
	NM_001202518.1	NP_001189447.1	8	7744
	NM_001202519.1	NP_001189448.1	9	8008
	NM_003879.5	NP_003870.4	10	7587
	XM_017005189.1	XP_016860678.1	11	8482
	XM_017005190.1	XP_016860679.1	10	7451
	XM_017005191.1	XP_016860680.1	10	7530
	XM_017005192.1	XP_016860681.1	10	8417
	XM_017005193.1	XP_016860682.1	10	10434
	XM_017005194.1	XP_016860683.1	10	8290
	XM_017005195.1	XP_016860684.1	11	7628
	XM_017005196.1	XP_016860685.1	8	7253
GenBank mRNA	AK125394.1	-	1	314

More Information

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
skeletal muscle tissue development
skeletal muscle atrophy
regulation of skeletal muscle satellite cell proliferation
skeletal myofibril assembly
viral process
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of I-kappaB kinase/NF-kappaB signaling
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
regulation of necroptotic process
execution phase of apoptosis
negative regulation of myoblast fusion
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
death receptor binding
protein binding
enzyme activator activity
protein complex binding
cysteine-type endopeptidase activity involved in execution phase of apoptosis