n347231

• Gene Symbol: ADAM10
• Gene Name: ADAM metallopeptidase domain 10
• Gene Aliases: AD10, AD18, CD156c, CDw156, HsT18717, MADM, RAK, kuz
• Chromosome Location: Chr.15: 58595204 - 58749978 on Build GRCh38
• UniGene ID: Hs.172028
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ADAM10
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001110.3	NP_001101.1	16	4296
	NM_001320570.1	NP_001307499.1	15	4203
	XM_017021861.1	XP_016877350.1	17	4351
GenBank mRNA	AY726599.1	-	1	433

Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID	Transcript Location
GenBankmRNA	AA234375.1	-	1	406		Chr. 15 - 58595901 - 58596347 [-] on Build GRCh38
GenBankmRNA	BE673819.1	-	1	157		Chr. 15 - 58595599 - 58596098 [-] on Build GRCh38
GenBankmRNA	EB386558.1	-	1	646		Chr. 15 - 58595810 - 58596587 [-] on Build GRCh38
GenBankmRNA	CD678645.1	-	1	450		Chr. 15 - 58595748 - 58596391 [-] on Build GRCh38

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: AK036883, AK036599, AK006577, AK036918, AK031857, and others.

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

in utero embryonic development
protein phosphorylation
membrane protein ectodomain proteolysis
negative regulation of cell adhesion
Notch signaling pathway
Notch receptor processing
integrin-mediated signaling pathway
cell-cell signaling
positive regulation of cell proliferation
positive regulation of T cell chemotaxis
protein processing
extracellular matrix disassembly
positive regulation of cell growth
positive regulation of cell migration
response to tumor necrosis factor
monocyte activation
ephrin receptor signaling pathway
PMA-inducible membrane protein ectodomain proteolysis
constitutive protein ectodomain proteolysis

Function(s)

endopeptidase activity
metalloendopeptidase activity
receptor binding
integrin binding
protein binding
metallopeptidase activity
zinc ion binding
SH3 domain binding
protein kinase binding
protein homodimerization activity