s11294 Validated

• Gene Symbol: PSEN2
• Gene Name: presenilin 2
• Gene Aliases: AD3L, AD4, CMD1V, PS2, STM2
• Chromosome Location: Chr.1: 226870572 - 226903829 on Build GRCh38
• UniGene ID: Hs.25363
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PSEN2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000447.2	NP_000438.2	13	1697
	NM_012486.2	NP_036618.2	13	1694
	XM_005273199.3	XP_005273256.1	12	1510
	XM_017001835.1	XP_016857324.1	12	2018
	XM_017001836.1	XP_016857325.1	12	1507
GenBank mRNA	AK292299.1	-	14	1646
	AK301143.1	-	12	1446
	BC006365.2	-	14	1891	4131408
	BT006984.1	-	11	1270
	L43964.1	-	12	1637
	L44577.1	-	13	1635
	U34349.1	-	11	1364

More Information

Matching Taqman Gene Expression Assay:

Hs01577197_m1

Panther Classification:

Molecular Function -

aspartic protease

Gene Ontology Categories:

Process(es)

response to hypoxia
membrane protein ectodomain proteolysis
calcium ion transport
Notch signaling pathway
Notch receptor processing
protein processing
membrane protein intracellular domain proteolysis
intracellular signal transduction
amyloid precursor protein catabolic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of catalytic activity
ephrin receptor signaling pathway
beta-amyloid metabolic process

Function(s)

endopeptidase activity
aspartic-type endopeptidase activity
protein binding