s1135 Validated

• Gene Symbol: ADSL
• Gene Name: adenylosuccinate lyase
• Gene Aliases: AMPS, ASASE, ASL
• Chromosome Location: Chr.22: 40346500 - 40387408 on Build GRCh38
• UniGene ID: Hs.75527
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ADSL
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000026.3	NP_000017.1	2	232
	NM_001123378.2	NP_001116850.1	2	232
	NM_001317923.1	NP_001304852.1	2	177
	NR_134256.1		2	232
	XM_011529977.2	XP_011528279.1	2	232
	XM_011529979.1	XP_011528281.1	2	232
	XM_011529980.2	XP_011528282.1	2	232
	XM_017028636.1	XP_016884125.1	2	214
	XM_017028637.1	XP_016884126.1	2	197
	XM_017028638.1	XP_016884127.1	2	214
	XM_017028639.1	XP_016884128.1	2	214
GenBank mRNA	AF067853.1	-	2	228
	AF067854.1	-	2	228
	AK225042.1	-	2	200
	AK291091.1	-	2	203
	AK293722.1	-	2	214
	AK298187.1	-	2	204
	AK300705.1	-	2	203
	BC000253.1	-	2	202	3352079
	BC018881.2	-	2	202
	BP298407.1	-	2	232
	CR456368.1	-	2	206
	KJ534763.1	-	2	173
	KJ535007.1	-	2	173
	KJ535020.1	-	2	173
	KJ535056.1	-	2	118
	S60710.1	-	2	175
	X65867.1	-	2	175

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_009634, AK051111, AK152092, AK168906, AK171725, and others.

Matching Taqman Gene Expression Assay:

Hs00163570_m1

Panther Classification:

Molecular Function -

lyase

Gene Ontology Categories:

Process(es)

purine nucleotide biosynthetic process
AMP biosynthetic process
'de novo' IMP biosynthetic process
purine ribonucleoside monophosphate biosynthetic process
'de novo' AMP biosynthetic process
protein tetramerization

Function(s)

N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity