s122009

Gene Symbol:

Tdg Gm9855

Gene Name:

thymine DNA glycosylase

thymine DNA glycosylase pseudogene

Gene Aliases:

E130317C12Rik, JZA-3, Jza1

ENSMUSG00000051559

Chromosome Location:

Chr.10: 82629247 - 82650494 on Build GRCm38

Chromosome Location:

Chr.10: 42052558 - 42055453 on Build GRCm38

UniGene ID:

Mm.284252

Mm.284252

Species:

Mouse

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: Tdg
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011561.2	NP_035691.2	7	844
	NM_172552.3	NP_766140.2	7	943
GenBank mRNA	AF102875.1	-	5	516
	AK053870.1	-	7	871
	AK164090.1	-	7	804
	AK164643.1	-	7	911
	AK169768.1	-	7	867
	BC010315.1	-	7	833	3595866
	BC085470.1	-	7	890	6416434
	BC085471.1	-	7	914	6816716

Gene Symbol: Gm9855
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AF069519.1	-	1	801
	AK089915.1	-	1	844

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_003211, BC019925, AK313234, AK309792, AK295387, and others.
This siRNA also targets the following transcripts in Rat: NM_053729, BC129088, AY026945.

Panther Classification:

Molecular Function -

DNA metabolism protein, DNA glycosylase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA repair
base-excision repair
mismatch repair
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
metabolic process
embryo development
chromatin modification
negative regulation of protein binding
negative regulation of chromatin binding
regulation of gene expression, epigenetic
DNA demethylation

Function(s)

RNA polymerase II transcription cofactor activity
double-stranded DNA binding
protein kinase C binding
protein binding
transcription factor binding
pyrimidine-specific mismatch base pair DNA N-glycosylase activity
hydrolase activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity, hydrolyzing N-glycosyl compounds
DNA N-glycosylase activity
protein domain specific binding
mismatched DNA binding
SUMO binding
protein homodimerization activity
structure-specific DNA binding