s135617

• Gene Symbol: Nfkb1
• Gene Name: nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• Gene Aliases: EBP-1, NF-kB
• Chromosome Location: Chr.2: 240773520 - 240890053 on Build Rnor_6.0
• UniGene ID: Rn.2411
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nfkb1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001276711.1	NP_001263640.1	12	1373
	XM_006233358.2	XP_006233420.1	10	1029
	XM_006233360.2	XP_006233422.1	10	1029

More Information

Panther Classification:

Molecular Function -

Rel homology transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
negative regulation of cytokine production
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
inflammatory response
response to oxidative stress
signal transduction
I-kappaB kinase/NF-kappaB signaling
response to bacterium
negative regulation of calcidiol 1-monooxygenase activity
response to cytokine
response to muscle stretch
NIK/NF-kappaB signaling
negative regulation of apoptotic process
negative regulation of interleukin-12 biosynthetic process
innate immune response
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to copper ion
negative regulation of inflammatory response
cellular response to lipopolysaccharide
cellular response to mechanical stimulus
cellular response to nicotine
cellular response to interleukin-1
cellular response to interleukin-6
cellular response to peptide hormone stimulus
positive regulation of canonical Wnt signaling pathway
positive regulation of hyaluronan biosynthetic process
positive regulation of miRNA metabolic process

Function(s)

regulatory region DNA binding
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
heat shock protein binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity