s13951

• Gene Symbol: TDG
• Gene Name: thymine DNA glycosylase
• Gene Aliases: hTDG
• Chromosome Location: Chr.12: 103965815 - 103988878 on Build GRCh38
• UniGene ID: Hs.584809
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TDG
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003211.4	NP_003202.3	4	681
	XM_005269125.1	XP_005269182.1	4	541
	XM_011538714.1	XP_011537016.1	3	511
	XM_011538715.1	XP_011537017.1	3	511
GenBank mRNA	AK295387.1	-	2	168
	AK303631.1	-	3	508
	AK309792.1	-	5	725
	AK313234.1	-	4	624
	BC019925.1	-	4	635
	BC037557.1	-	4	634	5184772

More Information

Panther Classification:

Molecular Function -

DNA metabolism protein, DNA glycosylase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
base-excision repair
base-excision repair, AP site formation
mismatch repair
transcription, DNA-templated
embryo development
covalent chromatin modification
protein sumoylation
negative regulation of protein binding
oxidative DNA demethylation
negative regulation of chromatin binding
regulation of gene expression, epigenetic
depyrimidination
DNA demethylation

Function(s)

RNA polymerase II transcription cofactor activity
damaged DNA binding
double-stranded DNA binding
uracil DNA N-glycosylase activity
protein kinase C binding
protein binding
pyrimidine-specific mismatch base pair DNA N-glycosylase activity
DNA N-glycosylase activity
mismatched DNA binding
SUMO binding
protein homodimerization activity
structure-specific DNA binding