s14605 Validated

• Gene Symbol: UBE3A
• Gene Name: ubiquitin protein ligase E3A
• Gene Aliases: ANCR, AS, E6-AP, EPVE6AP, HPVE6A
• Chromosome Location: Chr.15: 25337234 - 25439086 on Build GRCh38
• UniGene ID: Hs.598862
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: UBE3A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000462.3	NP_000453.2	10	2839
	NM_130838.1	NP_570853.1	6	2054
	NM_130839.2	NP_570854.1	9	2774
	XM_005268267.4	XP_005268324.1	11	3141
	XM_005268268.4	XP_005268325.1	10	3028
	XM_005268269.4	XP_005268326.1	11	2872
	XM_005268270.4	XP_005268327.1	10	2829
	XM_005268271.4	XP_005268328.1	7	2648
	XM_006720675.3	XP_006720738.1	11	3093
	XM_006720676.3	XP_006720739.1	8	2338
	XM_011521994.2	XP_011520296.1	11	3030
	XM_011521995.2	XP_011520297.1	11	2704
	XM_017022544.1	XP_016878033.1	12	3066
	XM_017022545.1	XP_016878034.1	11	3025
	XM_017022546.1	XP_016878035.1	11	2933
	XM_017022547.1	XP_016878036.1	10	2965
	XM_017022548.1	XP_016878037.1	10	2960
	XM_017022549.1	XP_016878038.1	10	2767
	XM_017022550.1	XP_016878039.1	10	2919
	XM_017022551.1	XP_016878040.1	11	2970
	XM_017022552.1	XP_016878041.1	11	2660
	XM_017022553.1	XP_016878042.1	11	2975
	XM_017022554.1	XP_016878043.1	7	2979
	XM_017022555.1	XP_016878044.1	9	2748
	XM_017022556.1	XP_016878045.1	10	2897
	XM_017022557.1	XP_016878046.1	9	2832
	XM_017022558.1	XP_016878047.1	10	3028
	XM_017022559.1	XP_016878048.1	7	2648
GenBank mRNA	AB194232.1	-	8	2150
	AF273050.1	-	7	2109
	AK130491.1	-	5	1783
	AK291405.1	-	7	2200
	AK292514.1	-	9	2384
	BC002582.2	-	9	2727	3160225
	BC009271.1	-	4	1331	3353595
	L07557.1	-	6	2076
	U84404.1	-	11	2596
	X98031.1	-	7	2079
	X98032.1	-	5	2010
	X98033.1	-	7	2070

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001191837, XM_008759399, XM_006229313, XM_006229310, XM_008759400, and others.
This siRNA also targets the following transcripts in Mouse: NM_011668, NM_173010, NM_001033962, AK083795, AK029133, and others.

Matching Taqman Gene Expression Assay:

Hs00166580_m1

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

ovarian follicle development
proteolysis
ubiquitin-dependent protein catabolic process
brain development
positive regulation of phosphatidylinositol 3-kinase signaling
viral process
androgen receptor signaling pathway
positive regulation of protein ubiquitination
sperm entry
regulation of circadian rhythm
positive regulation of transcription from RNA polymerase II promoter
protein autoubiquitination
prostate gland growth
protein K48-linked ubiquitination
regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

transcription coactivator activity
ubiquitin-protein transferase activity
protein binding
ligase activity
metal ion binding
ubiquitin protein ligase activity