s14606 Validated

• Gene Symbol: UBE3A
• Gene Name: ubiquitin protein ligase E3A
• Gene Aliases: ANCR, AS, E6-AP, EPVE6AP, HPVE6A
• Chromosome Location: Chr.15: 25337234 - 25439086 on Build GRCh38
• UniGene ID: Hs.598862
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: UBE3A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000462.3	NP_000453.2	7, 8	2383
	NM_130838.1	NP_570853.1	3, 4	1598
	NM_130839.2	NP_570854.1	6, 7	2318
	XM_005268267.4	XP_005268324.1	8, 9	2685
	XM_005268268.4	XP_005268325.1	7, 8	2572
	XM_005268269.4	XP_005268326.1	8, 9	2416
	XM_005268270.4	XP_005268327.1	7, 8	2373
	XM_005268271.4	XP_005268328.1	4, 5	2192
	XM_006720675.3	XP_006720738.1	8, 9	2637
	XM_006720676.3	XP_006720739.1	5, 6	1882
	XM_011521994.2	XP_011520296.1	8, 9	2574
	XM_011521995.2	XP_011520297.1	8, 9	2248
	XM_017022544.1	XP_016878033.1	9, 10	2610
	XM_017022545.1	XP_016878034.1	8, 9	2569
	XM_017022546.1	XP_016878035.1	8, 9	2477
	XM_017022547.1	XP_016878036.1	7, 8	2509
	XM_017022548.1	XP_016878037.1	7, 8	2504
	XM_017022549.1	XP_016878038.1	7, 8	2311
	XM_017022550.1	XP_016878039.1	7, 8	2463
	XM_017022551.1	XP_016878040.1	8, 9	2514
	XM_017022552.1	XP_016878041.1	8, 9	2204
	XM_017022553.1	XP_016878042.1	8, 9	2519
	XM_017022554.1	XP_016878043.1	4, 5	2523
	XM_017022555.1	XP_016878044.1	6, 7	2292
	XM_017022556.1	XP_016878045.1	7, 8	2441
	XM_017022557.1	XP_016878046.1	6, 7	2376
	XM_017022558.1	XP_016878047.1	7, 8	2572
	XM_017022559.1	XP_016878048.1	4, 5	2192
GenBank mRNA	AB194232.1	-	5, 6	1694
	AF273050.1	-	4, 5	1653
	AK130491.1	-	2, 3	1327
	AK291405.1	-	4, 5	1744
	AK292514.1	-	6, 7	1928
	BC002582.2	-	6, 7	2271	3160225
	BC009271.1	-	1, 2	875	3353595
	L07557.1	-	3, 4	1620
	U84404.1	-	8, 9	2140
	X98031.1	-	4, 5	1623
	X98032.1	-	2, 3	1554
	X98033.1	-	4, 5	1614

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001191837, XM_008759399, XM_006229313, XM_006229310, XM_008759400, and others.

Matching Taqman Gene Expression Assay:

Hs00166580_m1

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

ovarian follicle development
proteolysis
ubiquitin-dependent protein catabolic process
brain development
positive regulation of phosphatidylinositol 3-kinase signaling
viral process
androgen receptor signaling pathway
positive regulation of protein ubiquitination
sperm entry
regulation of circadian rhythm
positive regulation of transcription from RNA polymerase II promoter
protein autoubiquitination
prostate gland growth
protein K48-linked ubiquitination
regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

transcription coactivator activity
ubiquitin-protein transferase activity
protein binding
ligase activity
metal ion binding
ubiquitin protein ligase activity