s14735

• Gene Symbol: KDM6A
• Gene Name: lysine demethylase 6A
• Gene Aliases: KABUK2, UTX, bA386N14.2
• Chromosome Location: Chr.X: 44873175 - 45112612 on Build GRCh38
• UniGene ID: Hs.522616
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: KDM6A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001291415.1	NP_001278344.1	17	2443
	NM_001291416.1	NP_001278345.1	16	2308
	NM_001291417.1	NP_001278346.1	15	2152
	NM_001291418.1	NP_001278347.1	14	2050
	NM_001291421.1	NP_001278350.1	14	2031
	NM_021140.3	NP_066963.2	16	2287
	NR_111960.1		15	2206
	XM_005272656.4	XP_005272713.1	16	2341
	XM_005272659.4	XP_005272716.1	15	2185
	XM_011543957.2	XP_011542259.1	18	2500
	XM_011543958.2	XP_011542260.1	17	2443
	XM_011543959.2	XP_011542261.1	17	2398
	XM_011543960.2	XP_011542262.1	18	2500
	XM_011543961.2	XP_011542263.1	17	2365
	XM_011543962.2	XP_011542264.1	17	2344
	XM_011543963.2	XP_011542265.1	16	2308
	XM_011543964.2	XP_011542266.1	16	2287
	XM_011543965.2	XP_011542267.1	16	2263
	XM_011543966.2	XP_011542268.1	16	2242
	XM_011543967.2	XP_011542269.1	17	2344
	XM_011543968.2	XP_011542270.1	16	2209
	XM_011543969.2	XP_011542271.1	15	2206
	XM_011543970.2	XP_011542272.1	15	2185
	XM_011543971.2	XP_011542273.1	16	2263
	XM_011543972.2	XP_011542274.1	15	2152
	XM_011543973.2	XP_011542275.1	16	2209
	XM_011543974.1	XP_011542276.1	16	2287
	XM_011543975.2	XP_011542277.1	13	1613
	XM_017029782.1	XP_016885271.1	17	2365
	XM_017029783.1	XP_016885272.1	15	2206
	XM_017029784.1	XP_016885273.1	15	1753
	XM_017029785.1	XP_016885274.1	13	1726
GenBank mRNA	AB208795.1	-	16	2240
	AF000992.1	-	16	1936
	AF000993.1	-	16	1936
	AK294456.1	-	16	1883
	AK303430.1	-	5	891
	AK304114.1	-	15	2221
	AK307691.1	-	5	920
	AL831996.2	-	5	813
	BC093868.1	-	16	1933	7939713
	BC113381.1	-	16	1933	8322433
	BC143272.1	-	16	1954	9051774
	BC143277.1	-	17	2089	9051779
	BC143278.1	-	15	1798	9051780
	BX640694.1	-	4	692
	DQ062676.1	-	13	1579
	DQ062677.1	-	15	1673
	DQ062678.1	-	15	1775
	EU026283.1	-	16	1931
	EU026291.1	-	15	1829

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008773047.
This siRNA also targets the following transcripts in Mouse: NM_009483, AK080370, AJ002730, AK144654, BC053433, and others.

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

in utero embryonic development
neural tube closure
heart morphogenesis
respiratory system process
positive regulation of gene expression
somite rostral/caudal axis specification
multicellular organism growth
mesodermal cell differentiation
notochord morphogenesis
histone H3-K4 methylation
oxidation-reduction process
canonical Wnt signaling pathway
histone H3-K27 demethylation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
chromatin DNA binding
histone demethylase activity
identical protein binding
metal ion binding
dioxygenase activity
histone demethylase activity (H3-K27 specific)