s165740

• Gene Symbol: Dock2
• Gene Name: dedicator of cytokinesis 2
• Gene Aliases: -
• Chromosome Location: Chr.10: 19181512 - 19603173 on Build Rnor_6.0
• UniGene ID: Rn.178834
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Dock2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_008767630.1	XP_008765852.1	23	2431
GenBank mRNA	BC101877.1	-	23	2386

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_033374, AK172915, AK089228, AK089682, AK165765, and others.

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

membrane raft polarization
establishment of T cell polarity
immunological synapse formation
myeloid dendritic cell activation involved in immune response
chemotaxis
cytoskeleton organization
small GTPase mediated signal transduction
T cell proliferation
T cell activation
macropinocytosis
positive thymic T cell selection
negative thymic T cell selection
alpha-beta T cell activation
alpha-beta T cell proliferation
positive regulation of phagocytosis

Function(s)

Rac guanyl-nucleotide exchange factor activity
T cell receptor binding