s166221

• Gene Symbol: Prkdc
• Gene Name: protein kinase, DNA activated, catalytic polypeptide
• Gene Aliases: -
• Chromosome Location: Chr.11: 89293547 - 89510947 on Build Rnor_6.0
• UniGene ID: -
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Prkdc
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_003751100.3	XP_003751148.1	2, 3	498
	XM_008768933.1	XP_008767155.1	2, 3	499

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

telomere maintenance
double-strand break repair via homologous recombination
somitogenesis
negative regulation of protein phosphorylation
B cell lineage commitment
pro-B cell differentiation
T cell lineage commitment
immunoglobulin production
negative regulation of immunoglobulin production
positive regulation of immune system process
double-strand break repair
double-strand break repair via nonhomologous end joining
protein phosphorylation
brain development
heart development
intrinsic apoptotic signaling pathway in response to DNA damage
response to ionizing radiation
response to gamma radiation
response to activity
phosphorylation
peptidyl-serine phosphorylation
lymphocyte differentiation
protein destabilization
cellular response to insulin stimulus
T cell differentiation in thymus
V(D)J recombination
immunoglobulin V(D)J recombination
T cell receptor V(D)J recombination
ectopic germ cell programmed cell death
regulation of circadian rhythm
positive regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fibroblast proliferation
spleen development
thymus development
positive regulation of developmental growth
signal transduction involved in mitotic G1 DNA damage checkpoint
negative regulation of cellular senescence
negative regulation of response to gamma radiation

Function(s)

molecular_function
DNA binding
double-stranded DNA binding
protein serine/threonine kinase activity
DNA-dependent protein kinase activity
ATP binding
transcription factor binding
kinase activity
enzyme binding
poly(A) RNA binding