s17545

• Gene Symbol: ARHGEF2
• Gene Name: Rho/Rac guanine nucleotide exchange factor 2
• Gene Aliases: GEF, GEF-H1, GEFH1, LFP40, P40
• Chromosome Location: Chr.1: 155946839 - 155991263 on Build GRCh38
• UniGene ID: Hs.743352
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ARHGEF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001162383.1	NP_001155855.1	21	2853
	NM_001162384.1	NP_001155856.1	21	2850
	NM_004723.3	NP_004714.2	21	2778
	XM_005245587.2	XP_005245644.1	21	2906
	XM_005245588.2	XP_005245645.1	21	2903
	XM_005245589.4	XP_005245646.1	21	3059
	XM_005245590.3	XP_005245647.1	21	2781
	XM_005245591.3	XP_005245648.1	22	2897
	XM_005245592.2	XP_005245649.1	21	3050
	XM_005245593.4	XP_005245650.1	21	2781
	XM_005245594.2	XP_005245651.1	21	3767
	XM_006711622.3	XP_006711685.1	21	4044
	XM_006711623.3	XP_006711686.1	20	2780
	XM_006711624.3	XP_006711687.1	20	2807
	XM_006711625.3	XP_006711688.1	20	2713
	XM_006711626.2	XP_006711689.1	20	3699
	XM_011510136.2	XP_011508438.2	25	3462
	XM_011510137.2	XP_011508439.2	25	3465
	XM_011510139.2	XP_011508441.1	25	3465
	XM_011510141.2	XP_011508443.1	21	3583
	XM_011510143.2	XP_011508445.1	17	2329
	XM_017002794.1	XP_016858283.1	25	3462
	XM_017002795.1	XP_016858284.1	21	2797
	XM_017002796.1	XP_016858285.1	21	4041
	XM_017002797.1	XP_016858286.1	21	2781
	XM_017002798.1	XP_016858287.1	20	3976
	XM_017002799.1	XP_016858288.1	20	2777
GenBank mRNA	AB014551.3	-	25	3121
	AF486838.1	-	21	2732
	AL512715.1	-	21	2763
	AL832538.1	-	2	51
	BC020567.1	-	21	2835	4157775
	BT007407.1	-	20	2654
	U72206.1	-	21	2836
	X15610.1	-	7	844

More Information

Gene Ontology Categories:

Process(es)

establishment of mitotic spindle orientation
cell morphogenesis
intracellular protein transport
actin filament organization
negative regulation of microtubule depolymerization
mitotic nuclear division
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of cell proliferation
positive regulation of apoptotic process
positive regulation of GTPase activity
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of neurogenesis
regulation of small GTPase mediated signal transduction
positive regulation of NF-kappaB transcription factor activity
cell division
negative regulation of necroptotic process
cellular response to muramyl dipeptide
cellular response to tumor necrosis factor
cellular hyperosmotic response
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
microtubule binding
transcription factor binding
zinc ion binding
Rho GTPase binding
Rac guanyl-nucleotide exchange factor activity
Rac GTPase binding