s17547

• Gene Symbol: ARHGEF2
• Gene Name: Rho/Rac guanine nucleotide exchange factor 2
• Gene Aliases: GEF, GEF-H1, GEFH1, LFP40, P40
• Chromosome Location: Chr.1: 155946839 - 155991263 on Build GRCh38
• UniGene ID: Hs.743352
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ARHGEF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001162383.1	NP_001155855.1	14	1888
	NM_001162384.1	NP_001155856.1	14	1885
	NM_004723.3	NP_004714.2	14	1813
	XM_005245587.2	XP_005245644.1	14	1941
	XM_005245588.2	XP_005245645.1	14	1938
	XM_005245589.4	XP_005245646.1	14	2094
	XM_005245590.3	XP_005245647.1	14	1816
	XM_005245591.3	XP_005245648.1	15	1932
	XM_005245592.2	XP_005245649.1	14	2085
	XM_005245593.4	XP_005245650.1	14	1816
	XM_005245594.2	XP_005245651.1	14	2802
	XM_006711622.3	XP_006711685.1	14	3079
	XM_006711623.3	XP_006711686.1	13	1815
	XM_006711624.3	XP_006711687.1	13	1842
	XM_006711625.3	XP_006711688.1	13	1748
	XM_006711626.2	XP_006711689.1	13	2734
	XM_011510136.2	XP_011508438.2	18	2497
	XM_011510137.2	XP_011508439.2	18	2500
	XM_011510139.2	XP_011508441.1	18	2500
	XM_011510141.2	XP_011508443.1	14	2618
	XM_011510143.2	XP_011508445.1	10	1364
	XM_017002794.1	XP_016858283.1	18	2497
	XM_017002795.1	XP_016858284.1	14	1832
	XM_017002796.1	XP_016858285.1	14	3076
	XM_017002797.1	XP_016858286.1	14	1816
	XM_017002798.1	XP_016858287.1	13	3011
	XM_017002799.1	XP_016858288.1	13	1812
GenBank mRNA	AB014551.3	-	18	2156
	AF486838.1	-	14	1767
	AL512715.1	-	14	1798
	BC020567.1	-	14	1870	4157775
	BT007407.1	-	13	1689
	U72206.1	-	14	1875

More Information

Gene Ontology Categories:

Process(es)

establishment of mitotic spindle orientation
cell morphogenesis
intracellular protein transport
actin filament organization
negative regulation of microtubule depolymerization
mitotic nuclear division
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of cell proliferation
positive regulation of apoptotic process
positive regulation of GTPase activity
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of neurogenesis
regulation of small GTPase mediated signal transduction
positive regulation of NF-kappaB transcription factor activity
cell division
negative regulation of necroptotic process
cellular response to muramyl dipeptide
cellular response to tumor necrosis factor
cellular hyperosmotic response
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
microtubule binding
transcription factor binding
zinc ion binding
Rho GTPase binding
Rac guanyl-nucleotide exchange factor activity
Rac GTPase binding