s189804

Gene Symbol:

LOC100909750 Abl1

Gene Name:

tyrosine-protein kinase ABL1-like

ABL proto-oncogene 1, non-receptor tyrosine kinase

Gene Aliases:

-

Abl

Chromosome Location:

Chr.3: 9409198 - 9448279 on Build Rnor_6.0

Chromosome Location:

Chr.3: 10041820 - 10145076 on Build Rnor_6.0

UniGene ID:

-

Rn.3105

Species:

Rat

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: LOC100909750
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_003749439.3	XP_003749487.1		417

Gene Symbol: Abl1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001100850.1	NP_001094320.1	3	1620
	XM_006233918.2	XP_006233980.1	3	417
GenBank mRNA	DQ294401.1	-	3	362
	DQ294402.1	-	3	362

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001283046, NM_001283047, NM_009594, NM_001283045, NM_001112703, and others.

Gene Ontology Categories:

Process(es)

epidermal growth factor receptor signaling pathway
cell migration
cell differentiation
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
signal transduction in response to DNA damage
regulation of apoptotic process
innate immune response
platelet-derived growth factor receptor signaling pathway
B-1 B cell homeostasis
B cell proliferation involved in immune response
transitional one stage B cell differentiation
phagocytosis
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
response to oxidative stress
positive regulation of cytosolic calcium ion concentration
learning or memory
associative learning
peptidyl-tyrosine phosphorylation
cerebellum morphogenesis
negative regulation of cell-cell adhesion
microspike assembly
actin cytoskeleton organization
actin filament polymerization
negative regulation of BMP signaling pathway
regulation of actin cytoskeleton organization
positive regulation of osteoblast proliferation
substrate adhesion-dependent cell spreading
cellular response to oxidative stress
response to endoplasmic reticulum stress
B cell proliferation
response to drug
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of neuron apoptotic process
positive regulation of vasoconstriction
negative regulation of mitotic cell cycle
positive regulation of mitotic cell cycle
alpha-beta T cell differentiation
protein autophosphorylation
positive regulation of fibroblast proliferation
spleen development
thymus development
collateral sprouting
positive regulation of peptidyl-tyrosine phosphorylation
activated T cell proliferation
B cell receptor signaling pathway
neuromuscular process controlling balance
positive regulation of release of sequestered calcium ion into cytosol
positive regulation of oxidoreductase activity
negative regulation of ubiquitin-protein transferase activity
regulation of cell cycle
Bergmann glial cell differentiation
negative regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
cellular response to lipopolysaccharide
cellular response to transforming growth factor beta stimulus
response to epinephrine
negative regulation of protein serine/threonine kinase activity
actin filament branching
positive regulation of dendrite development
positive regulation of interleukin-2 secretion
negative regulation of phospholipase C activity
positive regulation of neuron death
positive regulation of hydrogen peroxide-mediated programmed cell death
positive regulation of interferon-gamma secretion
regulation of extracellular matrix organization
positive regulation of extracellular matrix organization
glomerular visceral epithelial cell apoptotic process
positive regulation of Wnt signaling pathway, planar cell polarity pathway
negative regulation of endothelial cell apoptotic process
regulation of cellular senescence
negative regulation of cellular senescence
regulation of response to DNA damage stimulus

Function(s)

non-membrane spanning protein tyrosine kinase activity
receptor binding
ATP binding
magnesium ion binding
protein kinase activity
protein tyrosine kinase activity
protein binding
protein C-terminus binding
kinase activity
SH3 domain binding
protein kinase binding
protein domain specific binding
syntaxin binding
manganese ion binding
actin filament binding
mitogen-activated protein kinase binding
proline-rich region binding
delta-catenin binding