s194731

• Gene Symbol: PTPRC
• Gene Name: protein tyrosine phosphatase, receptor type C
• Gene Aliases: B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
• Chromosome Location: Chr.1: 198638968 - 198757476 on Build GRCh38
• UniGene ID: Hs.654514
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PTPRC
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001267798.1	NP_001254727.1	2	277
	NM_002838.4	NP_002829.3	2	277
	NM_080921.3	NP_563578.2	2	277
	NR_052021.1		2	277
	XM_006711472.3	XP_006711535.1	2	238
	XM_006711473.3	XP_006711536.1	2	220
	XM_006711474.3	XP_006711537.1	2	220
GenBank mRNA	AK130573.1	-	2	150
	AK292131.1	-	2	150
	AK299986.1	-	2	150
	AK303539.1	-	2	150
	AK307635.1	-	2	155
	AK308217.1	-	2	226
	AK310898.1	-	2	173
	AY567999.1	-	1	78
	BC014239.2	-	2	141
	BC017863.1	-	2	149
	BC121086.1	-	1	87
	BC121087.1	-	1	87
	BC127656.1	-	1	87
	BC127657.1	-	1	87
	BC148257.1	-	1	87
	DA670254.1	-	2	180
	DA819314.1	-	2	277
	DA948670.1	-	2	240
	Y00062.1	-	3	204
	Y00638.1	-	2	144

More Information

Panther Classification:

Molecular Function -

protein phosphatase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of T cell mediated cytotoxicity
negative regulation of cytokine-mediated signaling pathway
hematopoietic progenitor cell differentiation
immunoglobulin biosynthetic process
negative regulation of protein kinase activity
protein dephosphorylation
negative regulation of cell adhesion involved in substrate-bound cell migration
cell surface receptor signaling pathway
dephosphorylation
T cell differentiation
positive regulation of B cell proliferation
peptidyl-tyrosine dephosphorylation
B cell proliferation
positive regulation of T cell proliferation
cell cycle phase transition
positive regulation of protein kinase activity
bone marrow development
stem cell development
T cell receptor signaling pathway
B cell receptor signaling pathway
positive regulation of antigen receptor-mediated signaling pathway
release of sequestered calcium ion into cytosol
defense response to virus
regulation of cell cycle
positive regulation of hematopoietic stem cell migration
positive regulation of stem cell proliferation

Function(s)

protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
protein binding
protein kinase binding