s197 Validated

• Gene Symbol: AURKA
• Gene Name: aurora kinase A
• Gene Aliases: AIK, ARK1, AURA, BTAK, PPP1R47, STK15, STK6, STK7
• Chromosome Location: Chr.20: 56369389 - 56392337 on Build GRCh38
• UniGene ID: Hs.250822
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: AURKA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001323303.1	NP_001310232.1	8	1311
	NM_001323304.1	NP_001310233.1	8	1074
	NM_001323305.1	NP_001310234.1	9	1184
	NM_003600.3	NP_003591.2	7	1201
	NM_198433.2	NP_940835.1	9	1409
	NM_198434.2	NP_940836.1	8	1100
	NM_198435.2	NP_940837.1	7	990
	NM_198436.2	NP_940838.1	8	1086
	NM_198437.2	NP_940839.1	7	976
	XM_017028034.1	XP_016883523.1	9	1531
	XM_017028035.1	XP_016883524.1	7	891
GenBank mRNA	AF008551.1	-	6	801
	AF011468.1	-	7	1057
	AK301769.1	-	7	663
	AK312776.1	-	7	868
	BC001280.1	-	8	933	3456017
	BC002499.2	-	7	929	3051177
	BC006423.1	-	7	826	3532438
	BC027464.1	-	8	968	4449474
	D84212.1	-	8	967

More Information

Matching Taqman Gene Expression Assay:

Hs00269212_m1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
meiotic spindle organization
protein phosphorylation
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
spindle organization
mitotic spindle organization
spindle assembly involved in female meiosis I
mitotic nuclear division
mitotic centrosome separation
anterior/posterior axis specification
anaphase-promoting complex-dependent catabolic process
regulation of protein stability
negative regulation of protein binding
response to estradiol
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of cytokinesis
histone-serine phosphorylation
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
positive regulation of mitotic nuclear division
regulation of centrosome cycle
protein autophosphorylation
cell division
centrosome localization
protein localization to centrosome
positive regulation of oocyte maturation
regulation of signal transduction by p53 class mediator
neuron projection extension

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein binding
ATP binding
protein kinase binding
ubiquitin protein ligase binding
histone serine kinase activity