s1997

• Gene Symbol: BLM
• Gene Name: Bloom syndrome RecQ like helicase
• Gene Aliases: BS, RECQ2, RECQL2, RECQL3
• Chromosome Location: Chr.15: 90717327 - 90815462 on Build GRCh38
• UniGene ID: Hs.725208
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BLM
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000057.3	NP_000048.1	21	4094
	NM_001287246.1	NP_001274175.1	22	4204
	NM_001287247.1	NP_001274176.1	19	3701
	NM_001287248.1	NP_001274177.1	21	4260
	XM_006720632.2	XP_006720695.1	15	2153
	XM_011521881.2	XP_011520183.1	18	3129
GenBank mRNA	AK295194.1	-	20	3160
	AK303159.1	-	15	2005
	AK314262.1	-	21	4023
	BC093622.1	-	21	4017	7939467
	BC101567.1	-	21	4017	8069073
	BC115030.1	-	21	4042	7961413
	BC115032.1	-	21	4042	7961425
	BC143280.1	-	21	4182	9051783
	U39817.1	-	21	4050

More Information

Panther Classification:

Molecular Function -

DNA helicase

Gene Ontology Categories:

Process(es)

regulation of cyclin-dependent protein serine/threonine kinase activity
double-strand break repair via homologous recombination
DNA double-strand break processing
DNA synthesis involved in DNA repair
strand displacement
DNA strand renaturation
DNA replication
DNA repair
DNA recombination
cellular response to DNA damage stimulus
mitotic G2 DNA damage checkpoint
response to X-ray
protein sumoylation
replication fork processing
DNA duplex unwinding
positive regulation of transcription, DNA-templated
negative regulation of DNA recombination
replication fork protection
protein oligomerization
negative regulation of cell division
cellular response to ionizing radiation
cellular response to hydroxyurea
cellular response to camptothecin
regulation of signal transduction by p53 class mediator

Function(s)

bubble DNA binding
p53 binding
single-stranded DNA binding
ATP-dependent DNA helicase activity
helicase activity
protein binding
ATP binding
ATP-dependent helicase activity
four-way junction helicase activity
ATPase activity
annealing helicase activity
ATP-dependent 3'-5' DNA helicase activity
G-quadruplex DNA binding