s21305 Validated

• Gene Symbol: HPSE
• Gene Name: heparanase
• Gene Aliases: HPA, HPA1, HPR1, HPSE1, HSE1
• Chromosome Location: Chr.4: 83292461 - 83335153 on Build GRCh38
• UniGene ID: Hs.44227
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HPSE
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001098540.2	NP_001092010.1	10	1373
	NM_001166498.2	NP_001159970.1	9	1189
	NM_001199830.1	NP_001186759.1	9	1131
	NM_006665.5	NP_006656.2	11	1411
GenBank mRNA	AF084467.1	-	10	1280
	AF144325.1	-	10	1373
	AF152376.1	-	10	1288
	AF155510.1	-	11	1410
	AF165154.1	-	10	1325
	AK075400.1	-	10	1337
	AK222986.1	-	10	1339
	AM419200.1	-	9	1100
	AY948074.1	-	10	1279
	BC051321.1	-	11	1411	6250265
	FJ517659.1	-	10	1242
	FJ517660.1	-	9	1068
	GQ337901.1	-	9	1189
	GQ337902.1	-	10	1296

More Information

Matching Taqman Gene Expression Assay:

Hs00180737_m1

Panther Classification:

Molecular Function -

glycosidase

Gene Ontology Categories:

Process(es)

carbohydrate metabolic process
glycosaminoglycan catabolic process
proteoglycan metabolic process
cell-matrix adhesion
positive regulation of vascular endothelial growth factor production
positive regulation of blood coagulation
extracellular matrix organization
heparan sulfate proteoglycan catabolic process
positive regulation of osteoblast proliferation
regulation of hair follicle development
positive regulation of hair follicle development
positive regulation of protein kinase B signaling
angiogenesis involved in wound healing
vascular wound healing

Function(s)

beta-glucuronidase activity
protein binding
heparanase activity
heparan sulfate proteoglycan binding
syndecan binding
protein dimerization activity