s218 Validated

• Gene Symbol: CDKN2A
• Gene Name: cyclin dependent kinase inhibitor 2A
• Gene Aliases: ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16
• Chromosome Location: Chr.9: 21967752 - 21995043 on Build GRCh38
• UniGene ID: Hs.512599
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CDKN2A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000077.4	NP_000068.1	3	922
	NM_001195132.1	NP_001182061.1	4	1119
	NM_058195.3	NP_478102.2	3	819
	NM_058197.4	NP_478104.2	3	890
	XM_005251343.1	XP_005251400.1	3	538
	XM_011517679.1	XP_011515981.1	3	689
GenBank mRNA	BC015960.2	-	3	709
	BC021998.2	-	3	709
	DQ318021.1	-	4	872
	JQ694043.1	-	3	656
	JQ694044.1	-	3	656
	JQ694045.1	-	3	656
	KF311101.1	-	1	1564
	L27211.1	-	3	656
	U26727.1	-	3	686
	U38945.1	-	3	819

More Information

Matching Taqman Gene Expression Assay:

Hs00233365_m1

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
negative regulation of cell-matrix adhesion
cell cycle arrest
Ras protein signal transduction
negative regulation of cell proliferation
negative regulation of cell growth
negative regulation of NF-kappaB transcription factor activity
positive regulation of smooth muscle cell apoptotic process
senescence-associated heterochromatin focus assembly
negative regulation of phosphorylation
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
cellular senescence
replicative senescence
positive regulation of macrophage apoptotic process
positive regulation of cellular senescence

Function(s)

cyclin-dependent protein serine/threonine kinase inhibitor activity
protein binding
protein kinase binding
poly(A) RNA binding
NF-kappaB binding