s223850

Gene Symbol:

HLA-J HLA-A HLA-G HLA-H

Gene Name:

major histocompatibility complex, class I, J (pseudogene)

major histocompatibility complex, class I, A

major histocompatibility complex, class I, G

major histocompatibility complex, class I, H (pseudogene)

Gene Aliases:

CDA12, D6S203, HLA-59, HLA-CDA12

Aw-33, Aw-74, HLA-A11, HLA-A33, HLA-DQB1, HLA-DRB1, HLAA

MHC-G

HLAHP

Chromosome Location:

Chr.6: 30005971 - 30009956 on Build GRCh38

Chromosome Location:

Chr.6: 29942470 - 29945884 on Build GRCh38

Chromosome Location:

Chr.6: 29826967 - 29831130 on Build GRCh38

Chromosome Location:

Chr.6: 29887760 - 29891080 on Build GRCh38

UniGene ID:

Hs.720762

Hs.181244

Hs.512152

Hs.728808

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

-

siRNA Details

Gene Symbol: HLA-J
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_024240.1		7	1533
GenBank mRNA	BC020891.1	-	6	1286

Gene Symbol: HLA-A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002116.7	NP_002107.3	8	1577
GenBank mRNA	AK130165.1	-	8	1532
	BC019236.2	-	8	1498	2821717
	BE875389.1	-	3	490
	D32129.1	-	8	1498
	M24095.1	-	7	1415
	X02457.1	-	7	1379

Gene Symbol: HLA-G
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002127.5	NP_002118.1	8	1554
	XM_017010816.1	XP_016866305.1	8	1463
	XM_017010817.1	XP_016866306.1	6	1109
GenBank mRNA	AL551999.3	-	3	458

Gene Symbol: HLA-H
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_001434.3		8	1478
GenBank mRNA	AK090500.1	-	6	2272

More Information

Panther Classification:

Molecular Function -

major histocompatibility complex protein

Gene Ontology Categories:

Process(es)

antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
viral process
antigen processing and presentation
regulation of immune response
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
positive regulation of tolerance induction
positive regulation of T cell tolerance induction
immune response-inhibiting cell surface receptor signaling pathway
cellular defense response
positive regulation of interleukin-12 production
negative regulation of T cell proliferation
positive regulation of regulatory T cell differentiation
negative regulation of immune response
negative regulation of dendritic cell differentiation
immune response

Function(s)

protein binding
beta-2-microglobulin binding
peptide antigen binding
poly(A) RNA binding
antigen binding
receptor binding
protein homodimerization activity