s224161

• Gene Symbol: NOX4
• Gene Name: NADPH oxidase 4
• Gene Aliases: KOX, KOX-1, RENOX
• Chromosome Location: Chr.11: 89324353 - 89589611 on Build GRCh38
• UniGene ID: Hs.371036
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NOX4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001143836.2	NP_001137308.1	10, 11	1324
	NM_001143837.1	NP_001137309.1	13, 14	1469
	NM_001291926.1	NP_001278855.1	10, 11	1320
	NM_001291927.1	NP_001278856.1	10, 11	1074
	NM_001291929.1	NP_001278858.1	9, 10	987
	NM_001300995.1	NP_001287924.1	10, 11	1047
	NM_016931.4	NP_058627.1	10, 11	1324
	XM_006718849.3	XP_006718912.1	10, 11	1252
	XM_011542857.2	XP_011541159.1	10, 11	1124
	XM_017017841.1	XP_016873330.1	9, 10	1171
	XM_017017842.1	XP_016873331.1	6, 7	623
	XM_017017843.1	XP_016873332.1	10, 11	1252
	XM_017017844.1	XP_016873333.1	11, 12	1310
	XM_017017845.1	XP_016873334.1	7, 8	726
GenBank mRNA	AB041035.1	-	10, 11	1244
	AF254621.1	-	10, 11	1091
	AF261943.1	-	10, 11	1005
	AJ704725.1	-	10, 11	1001
	AJ704726.1	-	10, 11	1005
	AK057189.1	-	13, 14	1469
	AK291830.1	-	10, 11	1087
	AK298323.1	-	10, 11	1018
	AK298328.1	-	10, 11	1074
	AK298357.1	-	9, 10	978
	AK298376.1	-	6, 7	765
	AY288918.1	-	10, 11	1005
	BC040105.1	-	10, 11	1077	5590269

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: BC138918, AF276957, AF218723, BC145462, BC021378.

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
cell morphogenesis
response to hypoxia
superoxide metabolic process
inflammatory response
cell aging
negative regulation of cell proliferation
gene expression
positive regulation of smooth muscle cell migration
superoxide anion generation
positive regulation of apoptotic process
positive regulation of MAP kinase activity
bone resorption
homocysteine metabolic process
positive regulation of stress fiber assembly
positive regulation of protein kinase B signaling
cardiac muscle cell differentiation
oxidation-reduction process
positive regulation of ERK1 and ERK2 cascade
cellular response to cAMP
cellular response to glucose stimulus
cellular response to gamma radiation
cellular response to transforming growth factor beta stimulus
reactive oxygen species metabolic process
positive regulation of reactive oxygen species metabolic process
positive regulation of DNA biosynthetic process

Function(s)

nucleotide binding
protein binding
electron carrier activity
NAD(P)H oxidase activity
superoxide-generating NADPH oxidase activity
oxygen sensor activity
heme binding
flavin adenine dinucleotide binding
modified amino acid binding