s224206

• Gene Symbol: PDE4D
• Gene Name: phosphodiesterase 4D
• Gene Aliases: ACRDYS2, DPDE3, HSPDE4D, PDE43, PDE4DN2, STRK1
• Chromosome Location: Chr.5: 58969038 - 60488098 on Build GRCh38
• UniGene ID: Hs.117545
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PDE4D
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001104631.1	NP_001098101.1	5, 6	980
	NM_001165899.1	NP_001159371.1	7, 8	871
	NM_001197218.1	NP_001184147.1	5, 6	719
	NM_001197219.1	NP_001184148.1	5, 6	497
	NM_001197220.1	NP_001184149.1	5, 6	1135
	NM_006203.4	NP_006194.2	5, 6	523
	XM_005248537.3	XP_005248594.1	5, 6	1677
	XM_005248538.4	XP_005248595.1	6, 7	3578
	XM_011543469.1	XP_011541771.1	8, 9	960
	XM_011543470.2	XP_011541772.1	8, 9	884
	XM_011543471.1	XP_011541773.1	7, 8	837
	XM_011543473.1	XP_011541775.1	7, 8	785
	XM_011543477.2	XP_011541779.1	7, 8	787
	XM_017009565.1	XP_016865054.1	8, 9	997
	XM_017009566.1	XP_016865055.1	8, 9	887
	XM_017009567.1	XP_016865056.1	6, 7	625
	XM_017009568.1	XP_016865057.1	8, 9	871
	XM_017009569.1	XP_016865058.1	7, 8	750
	XM_017009570.1	XP_016865059.1	4, 5	1570
	XM_017009571.1	XP_016865060.1	7, 8	793
GenBank mRNA	AF012073.1	-	5, 6	733
	AF536977.1	-	5, 6	497
	AY245866.1	-	7, 8	836
	AY245867.1	-	5, 6	1135
	AY388960.1	-	5, 6	418
	L20970.1	-	5, 6	531
	U02882.1	-	4, 5	301
	U50159.1	-	5, 6	474

More Information

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

regulation of heart rate
cAMP catabolic process
smooth muscle contraction
aging
regulation of receptor activity
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
cAMP-mediated signaling
neutrophil chemotaxis
regulation of cAMP metabolic process
positive regulation of interferon-gamma production
positive regulation of interleukin-2 production
positive regulation of interleukin-5 production
negative regulation of peptidyl-serine phosphorylation
multicellular organism growth
negative regulation of heart contraction
T cell receptor signaling pathway
regulation of ryanodine-sensitive calcium-release channel activity
establishment of endothelial barrier
cellular response to lipopolysaccharide
cellular response to epinephrine stimulus
adrenergic receptor signaling pathway
regulation of cardiac muscle cell contraction
adrenergic receptor signaling pathway involved in positive regulation of heart rate
regulation of cell communication by electrical coupling involved in cardiac conduction
negative regulation of relaxation of cardiac muscle

Function(s)

3',5'-cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
protein binding
drug binding
enzyme binding
cAMP binding
beta-2 adrenergic receptor binding
ion channel binding
metal ion binding
ATPase binding
scaffold protein binding