s227305

• Gene Symbol: ATR
• Gene Name: ATR serine/threonine kinase
• Gene Aliases: FCTCS, FRP1, MEC1, SCKL, SCKL1
• Chromosome Location: Chr.3: 142449235 - 142578826 on Build GRCh38
• UniGene ID: Hs.271791
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ATR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001184.3	NP_001175.2	43	7364
	XM_011512924.1	XP_011511226.1	43	7337
	XM_011512925.1	XP_011511227.1	42	7145
	XM_017006643.1	XP_016862132.1	42	7139
GenBank mRNA	AB208847.1	-	6	781
	U49844.1	-	43	7347
	U76308.1	-	43	7321
	Y09077.1	-	43	7321

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_003750561, XM_008766572, XM_006243600.
This siRNA also targets the following transcripts in Mouse: NM_019864, AK132223, AF236887, AK220176.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
DNA replication
DNA repair
cellular response to DNA damage stimulus
cell cycle
multicellular organism development
negative regulation of DNA replication
peptidyl-serine phosphorylation
positive regulation of telomere maintenance via telomerase
cellular response to UV
interstrand cross-link repair
response to drug
positive regulation of DNA damage response, signal transduction by p53 class mediator
protein autophosphorylation
protein localization to chromosome, telomeric region
cellular response to gamma radiation
replicative senescence
establishment of RNA localization to telomere
establishment of macromolecular complex localization to telomere
regulation of cellular response to heat
regulation of signal transduction by p53 class mediator
positive regulation of telomerase catalytic core complex assembly

Function(s)

DNA binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
MutLalpha complex binding
MutSalpha complex binding