s22844

• Gene Symbol: CNOT1
• Gene Name: CCR4-NOT transcription complex subunit 1
• Gene Aliases: AD-005, CDC39, NOT1, NOT1H
• Chromosome Location: Chr.16: 58519946 - 58629886 on Build GRCh38
• UniGene ID: Hs.460923
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CNOT1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001265612.1	NP_001252541.1	20	2875
	NM_016284.4	NP_057368.3	20	2890
	NM_206999.2	NP_996882.1	20	2890
	NR_049763.1		20	2875
GenBank mRNA	AB023224.2	-	7	935
	AK056927.1	-	11	1425
	AL832769.1	-	20	2839
	BC024317.1	-	3	289
	BC040523.1	-	20	2842	5266600
	BX537840.1	-	20	2821
	BX647815.1	-	20	2830
	CR749237.1	-	13	1830
	EF553522.1	-	20	2824

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001134840, XM_008772271, XM_008772272, BC168171.

Panther Classification:

Molecular Function -

mRNA polyadenylation factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
nuclear-transcribed mRNA poly(A) tail shortening
transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
multicellular organism development
positive regulation of cytoplasmic mRNA processing body assembly
negative regulation of translation
negative regulation of intracellular estrogen receptor signaling pathway
gene silencing by miRNA
negative regulation of retinoic acid receptor signaling pathway
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of mRNA catabolic process
RNA phosphodiester bond hydrolysis, exonucleolytic
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
regulation of stem cell population maintenance

Function(s)

poly(A)-specific ribonuclease activity
protein binding
protein domain specific binding
estrogen receptor binding
protein complex scaffold
retinoic acid receptor binding
poly(A) RNA binding
armadillo repeat domain binding