s229659

• Gene Symbol: DIS3
• Gene Name: DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
• Gene Aliases: 2810028N01Rik, EXOSC11, KIAA1008, RRP44, dis3p
• Chromosome Location: Chr.13: 72755402 - 72782128 on Build GRCh38
• UniGene ID: Hs.744104
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DIS3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001128226.2	NP_001121698.1	19	2734
	NM_001322348.1	NP_001309277.1	18	2666
	NM_001322349.1	NP_001309278.1	20	2892
	NM_014953.4	NP_055768.3	19	2824
GenBank mRNA	AB001743.1	-	19	2555
	AB023225.1	-	19	2531
	AF330044.1	-	19	2564
	AK001346.1	-	3	245
	AK314715.1	-	19	2640
	AL080158.1	-	13	1551
	AL832266.1	-	19	2617
	BC038101.1	-	20	2863	4827328
	BC056143.1	-	19	2629	5505671

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001127483, XM_006252391, XM_008770869, FQ210067, BC166824.
This siRNA also targets the following transcripts in Mouse: NM_028315, AK038313, BC027357, AK032091.

Panther Classification:

Molecular Function -

exoribonuclease

Gene Ontology Categories:

Process(es)

rRNA processing
mRNA catabolic process
rRNA catabolic process
regulation of mRNA stability
positive regulation of GTPase activity
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
CUT catabolic process
RNA phosphodiester bond hydrolysis, exonucleolytic

Function(s)

3'-5'-exoribonuclease activity
RNA binding
endonuclease activity
guanyl-nucleotide exchange factor activity
protein binding