s229682

Gene Symbol:

HLA-J HLA-G HLA-K

Gene Name:

major histocompatibility complex, class I, J (pseudogene)

major histocompatibility complex, class I, G

major histocompatibility complex, class I, K (pseudogene)

Gene Aliases:

CDA12, D6S203, HLA-59, HLA-CDA12

MHC-G

HLA-70, HLA70, HLAK

Chromosome Location:

Chr.6: 30005971 - 30009956 on Build GRCh38

Chromosome Location:

Chr.6: 29826967 - 29831130 on Build GRCh38

Chromosome Location:

Chr.6: 29926659 - 29929839 on Build GRCh38

UniGene ID:

Hs.720762

Hs.512152

Hs.728972

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: HLA-J
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_024240.1		7	1445
GenBank mRNA	BC020891.1	-	6	1198
	BC062324.1	-	5	851
	BC089454.1	-	6	1133

Gene Symbol: HLA-G
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002127.5	NP_002118.1	8	1467
	XM_017010816.1	XP_016866305.1	8	1376
	XM_017010817.1	XP_016866306.1	6	1022
GenBank mRNA	BC021708.2	-	10	1390	4822521

Gene Symbol: HLA-K
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	BC035647.1	-	5	1655

More Information

Panther Classification:

Molecular Function -

major histocompatibility complex protein

Gene Ontology Categories:

Process(es)

antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
positive regulation of tolerance induction
positive regulation of T cell tolerance induction
immune response-inhibiting cell surface receptor signaling pathway
cellular defense response
antigen processing and presentation
positive regulation of interleukin-12 production
negative regulation of T cell proliferation
positive regulation of regulatory T cell differentiation
regulation of immune response
negative regulation of immune response
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
negative regulation of dendritic cell differentiation

Function(s)

antigen binding
receptor binding
peptide antigen binding
protein homodimerization activity