s27659

• Gene Symbol: PLCE1
• Gene Name: phospholipase C epsilon 1
• Gene Aliases: NPHS3, PLCE, PPLC
• Chromosome Location: Chr.10: 93993989 - 94329447 on Build GRCh38
• UniGene ID: Hs.655033
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PLCE1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001165979.2	NP_001159451.1	16	3510
	NM_001288989.1	NP_001275918.1	17	4951
	NM_016341.3	NP_057425.3	17	4999
	XM_006717885.3	XP_006717948.1	17	4947
	XM_006717888.3	XP_006717951.1	17	4947
	XM_006717889.3	XP_006717952.1	17	4899
	XM_006717890.2	XP_006717953.1	16	3463
	XM_011539849.2	XP_011538151.1	17	6104
	XM_011539850.2	XP_011538152.1	16	4592
	XM_011539851.2	XP_011538153.1	17	4949
	XM_011539852.2	XP_011538154.1	17	4949
	XM_017016310.1	XP_016871799.1	18	4994
	XM_017016311.1	XP_016871800.1	17	4947
	XM_017016312.1	XP_016871801.1	16	3415
GenBank mRNA	AB040949.2	-	17	4999
	AF117948.1	-	8	1074
	AF170071.1	-	16	3441
	AK289852.1	-	16	3463
	BC140705.1	-	16	4425	9021573
	BC144286.1	-	16	4377	9052806
	BC151854.1	-	17	4999	8860521

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053758, XM_008760360, XM_008760361, AF323615.

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor, phospholipase

Gene Ontology Categories:

Process(es)

activation of MAPK activity
regulation of cell growth
phospholipid metabolic process
diacylglycerol biosynthetic process
regulation of smooth muscle contraction
cytoskeleton organization
epidermal growth factor receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
Ras protein signal transduction
heart development
regulation of G-protein coupled receptor protein signaling pathway
cell proliferation
lipid catabolic process
calcium-mediated signaling
glomerulus development
positive regulation of GTPase activity
inositol phosphate metabolic process
regulation of protein kinase activity
regulation of Ras protein signal transduction
inositol phosphate-mediated signaling

Function(s)

phosphatidylinositol phospholipase C activity
phospholipase C activity
receptor signaling protein activity
guanyl-nucleotide exchange factor activity
protein binding
Ras GTPase binding
enzyme binding