s27660 Validated

• Gene Symbol: PLCE1
• Gene Name: phospholipase C epsilon 1
• Gene Aliases: NPHS3, PLCE, PPLC
• Chromosome Location: Chr.10: 93993989 - 94329447 on Build GRCh38
• UniGene ID: Hs.655033
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PLCE1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001165979.2	NP_001159451.1	2	529
	NM_001288989.1	NP_001275918.1	3	2018
	NM_016341.3	NP_057425.3	3	2018
	XM_006717885.3	XP_006717948.1	3	1966
	XM_006717888.3	XP_006717951.1	3	1966
	XM_006717889.3	XP_006717952.1	3	1966
	XM_006717890.2	XP_006717953.1	2	482
	XM_011539849.2	XP_011538151.1	3	3123
	XM_011539850.2	XP_011538152.1	2	1611
	XM_011539851.2	XP_011538153.1	3	1968
	XM_011539852.2	XP_011538154.1	3	1968
	XM_017016310.1	XP_016871799.1	4	2013
	XM_017016311.1	XP_016871800.1	3	1966
	XM_017016312.1	XP_016871801.1	2	482
GenBank mRNA	AB040949.2	-	3	2018
	AF170071.1	-	2	460
	AF190642.2	-	2	1619
	AK289852.1	-	2	482
	AK297779.1	-	2	269
	BC140705.1	-	2	1444	9021573
	BC144286.1	-	2	1444	9052806
	BC151854.1	-	3	2018	8860521

More Information

Matching Taqman Gene Expression Assay:

Hs00275279_m1

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor, phospholipase

Gene Ontology Categories:

Process(es)

activation of MAPK activity
regulation of cell growth
phospholipid metabolic process
diacylglycerol biosynthetic process
regulation of smooth muscle contraction
cytoskeleton organization
epidermal growth factor receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
Ras protein signal transduction
heart development
regulation of G-protein coupled receptor protein signaling pathway
cell proliferation
lipid catabolic process
calcium-mediated signaling
glomerulus development
positive regulation of GTPase activity
inositol phosphate metabolic process
regulation of protein kinase activity
regulation of Ras protein signal transduction
inositol phosphate-mediated signaling

Function(s)

phosphatidylinositol phospholipase C activity
phospholipase C activity
receptor signaling protein activity
guanyl-nucleotide exchange factor activity
protein binding
Ras GTPase binding
enzyme binding