s346 Validated

• Gene Symbol: VAV3
• Gene Name: vav guanine nucleotide exchange factor 3
• Gene Aliases: -
• Chromosome Location: Chr.1: 107571160 - 107964923 on Build GRCh38
• UniGene ID: Hs.267659
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: VAV3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001079874.1	NP_001073343.1	3	195
	NM_006113.4	NP_006104.4	20	1856
	XM_005270360.2	XP_005270417.1	19	1668
	XM_017000053.1	XP_016855542.1	18	1777
	XM_017000054.1	XP_016855543.1	20	1849
	XM_017000055.1	XP_016855544.1	19	1526
	XM_017000056.1	XP_016855545.1	9	732
GenBank mRNA	AF035442.1	-	3	196
	AF067817.1	-	20	1839
	AF118886.1	-	19	1660
	AF118887.1	-	20	1848
	AK296537.1	-	2	216
	AK300474.1	-	2	150
	AK304088.1	-	3	195
	AK316295.1	-	3	195
	BC143969.1	-	20	1939	9052487

More Information

Matching Taqman Gene Expression Assay:

Hs00196125_m1

Gene Ontology Categories:

Process(es)

angiogenesis
vesicle fusion
cellular response to DNA damage stimulus
integrin-mediated signaling pathway
small GTPase mediated signal transduction
regulation of cell size
positive regulation of signal transduction
lamellipodium assembly
platelet activation
neutrophil chemotaxis
positive regulation of B cell proliferation
regulation of Rho protein signal transduction
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
response to drug
positive regulation of apoptotic process
regulation of GTPase activity
positive regulation of GTPase activity
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of cell adhesion
vascular endothelial growth factor receptor signaling pathway
ephrin receptor signaling pathway
B cell receptor signaling pathway
regulation of small GTPase mediated signal transduction

Function(s)

SH3/SH2 adaptor activity
guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
epidermal growth factor receptor binding
protein binding
Rac guanyl-nucleotide exchange factor activity
metal ion binding