s4119 Validated

• Gene Symbol: DLG1
• Gene Name: discs large MAGUK scaffold protein 1
• Gene Aliases: DLGH1, SAP-97, SAP97, dJ1061C18.1.1, hdlg
• Chromosome Location: Chr.3: 197042560 - 197299272 on Build GRCh38
• UniGene ID: Hs.292549
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DLG1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001098424.1	NP_001091894.1	9, 10	1001
	NM_001204386.1	NP_001191315.1	8, 9	902
	NM_001204387.1	NP_001191316.1	4, 5	786
	NM_001204388.1	NP_001191317.1	4, 5	786
	NM_001290983.1	NP_001277912.1	9, 10	1070
	NM_004087.2	NP_004078.2	9, 10	1001
	XM_005269289.3	XP_005269346.1	9, 10	1283
	XM_011512502.2	XP_011510804.1	9, 10	1283
	XM_011512503.1	XP_011510805.1	8, 9	1181
	XM_011512505.1	XP_011510807.1	8, 9	1181
	XM_011512506.1	XP_011510808.1	7, 8	1127
	XM_011512509.1	XP_011510811.1	8, 9	1181
	XM_017005800.1	XP_016861289.1	9, 10	1418
	XM_017005801.1	XP_016861290.1	9, 10	938
	XM_017005802.1	XP_016861291.1	9, 10	1008
	XM_017005803.1	XP_016861292.1	9, 10	929
	XM_017005804.1	XP_016861293.1	9, 10	1283
	XM_017005805.1	XP_016861294.1	9, 10	1100
	XM_017005806.1	XP_016861295.1	8, 9	1181
	XM_017005807.1	XP_016861296.1	8, 9	1280
	XM_017005808.1	XP_016861297.1	8, 9	839
	XM_017005809.1	XP_016861298.1	8, 9	941
	XM_017005810.1	XP_016861299.1	8, 9	839
	XM_017005811.1	XP_016861300.1	7, 8	1127
	XM_017005812.1	XP_016861301.1	7, 8	781
	XM_017005813.1	XP_016861302.1	7, 8	785
	XM_017005814.1	XP_016861303.1	7, 8	888
	XM_017005815.1	XP_016861304.1	7, 8	1127
	XM_017005816.1	XP_016861305.1	8, 9	1280
	XM_017005817.1	XP_016861306.1	8, 9	811
	XM_017005818.1	XP_016861307.1	8, 9	913
	XM_017005819.1	XP_016861308.1	8, 9	830
	XM_017005820.1	XP_016861309.1	7, 8	845
	XM_017005821.1	XP_016861310.1	5, 6	3286
	XM_017005822.1	XP_016861311.1	5, 6	3288
	XM_017005823.1	XP_016861312.1	4, 5	3183
GenBank mRNA	AB209536.2	-	1, 2	124
	AK293967.1	-	4, 5	505
	AK294772.1	-	4, 5	513
	AK294855.1	-	4, 5	786
	AK304280.1	-	7, 8	848
	AK310596.1	-	8, 9	840
	AK310893.1	-	9, 10	1285
	AK311129.1	-	3, 4	238
	BC015560.2	-	9, 10	1240
	BC028486.1	-	9, 10	1240
	BC140841.1	-	9, 10	966	9021709
	BC144651.1	-	8, 9	867	9053182
	EF553524.1	-	9, 10	1070
	U13896.1	-	9, 10	999
	U13897.1	-	9, 10	999

More Information

Matching Taqman Gene Expression Assay:

Hs00177739_m1

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
branching involved in ureteric bud morphogenesis
immunological synapse formation
endothelial cell proliferation
lens development in camera-type eye
T cell cytokine production
protein dephosphorylation
actin filament organization
mitotic cell cycle checkpoint
establishment or maintenance of cell polarity
chemical synaptic transmission
nervous system development
positive regulation of cell proliferation
regulation of cell shape
viral process
single organismal cell-cell adhesion
peristalsis
positive regulation of actin filament polymerization
cortical actin cytoskeleton organization
astral microtubule organization
membrane raft organization
regulation of myelination
activation of protein kinase activity
ion transmembrane transport
cellular protein complex localization
T cell activation
negative regulation of T cell proliferation
regulation of membrane potential
amyloid precursor protein metabolic process
receptor clustering
positive regulation of potassium ion transport
cortical microtubule organization
establishment or maintenance of epithelial cell apical/basal polarity
negative regulation of mitotic cell cycle
GMP metabolic process
GDP metabolic process
reproductive structure development
embryonic skeletal system morphogenesis
smooth muscle tissue development
negative regulation of epithelial cell proliferation
establishment of centrosome localization
negative regulation of protein kinase B signaling
hard palate development
negative regulation of ERK1 and ERK2 cascade
bicellular tight junction assembly
protein localization to plasma membrane
positive regulation of establishment of protein localization to plasma membrane
receptor localization to synapse
regulation of NIK/NF-kappaB signaling
regulation of sodium ion transmembrane transport
negative regulation of p38MAPK cascade

Function(s)

guanylate kinase activity
phosphoprotein phosphatase activity
protein binding
protein C-terminus binding
cytoskeletal protein binding
ligand-gated ion channel activity
potassium channel regulator activity
protein kinase binding
phosphatase binding
mitogen-activated protein kinase kinase binding
protein complex scaffold
ionotropic glutamate receptor binding
ion channel binding
L27 domain binding
cadherin binding involved in cell-cell adhesion