s4221 Validated

• Gene Symbol: DNMT3B
• Gene Name: DNA methyltransferase 3 beta
• Gene Aliases: ICF, ICF1, M.HsaIIIB
• Chromosome Location: Chr.20: 32762385 - 32809356 on Build GRCh38
• UniGene ID: Hs.643024
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DNMT3B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001207055.1	NP_001193984.1	7	1085
	NM_001207056.1	NP_001193985.1	6	983
	NM_006892.3	NP_008823.1	8	1211
	NM_175848.1	NP_787044.1	8	1211
	NM_175849.1	NP_787045.1	8	1211
	NM_175850.2	NP_787046.1	8	1190
	XM_011528653.2	XP_011526955.1	8	1063
	XM_011528654.2	XP_011526956.1	7	938
GenBank mRNA	AB208880.1	-	8	1189
	AF156487.1	-	8	1004
	AF156488.1	-	8	1004
	AF176228.1	-	8	1190
	AF331857.1	-	8	1211
	AK001191.1	-	1	83
	AK295176.1	-	7	852
	AK299776.1	-	7	824
	AK299821.1	-	6	726
	AK299915.1	-	7	862
	AK300857.1	-	7	874
	DQ321787.1	-	8	1211

More Information

Matching Taqman Gene Expression Assay:

Hs00171876_m1

Panther Classification:

Molecular Function -

DNA methyltransferase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
response to hypoxia
DNA methylation
response to toxic substance
response to ionizing radiation
DNA methylation on cytosine within a CG sequence
positive regulation of gene expression
response to activity
response to caffeine
response to estradiol
response to vitamin A
response to cocaine
response to drug
positive regulation of neuron differentiation
negative regulation of gene expression, epigenetic
S-adenosylhomocysteine metabolic process
S-adenosylmethioninamine metabolic process
positive regulation of histone H3-K4 methylation
negative regulation of histone H3-K9 methylation
cellular response to hyperoxia
cellular response to dexamethasone stimulus
C-5 methylation of cytosine

Function(s)

chromatin binding
transcription corepressor activity
DNA (cytosine-5-)-methyltransferase activity
protein binding
DNA-methyltransferase activity
histone deacetylase binding
unmethylated CpG binding
metal ion binding
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates