s530955

• Gene Symbol: PSEN2
• Gene Name: presenilin 2
• Gene Aliases: AD3L, AD4, CMD1V, PS2, STM2
• Chromosome Location: Chr.1: 226870572 - 226903829 on Build GRCh38
• UniGene ID: Hs.25363
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PSEN2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000447.2	NP_000438.2	7	947
	NM_012486.2	NP_036618.2	7	947
	XM_005273199.3	XP_005273256.1	6	760
	XM_017001835.1	XP_016857324.1	6	1268
	XM_017001836.1	XP_016857325.1	6	760
GenBank mRNA	AF416718.1	-	5	588
	AK292299.1	-	8	899
	AK301143.1	-	6	696
	BC006365.2	-	8	1141	4131408
	BT006984.1	-	5	520
	L43964.1	-	6	887
	L44577.1	-	7	885
	U34349.1	-	5	611

More Information

Panther Classification:

Molecular Function -

aspartic protease

Gene Ontology Categories:

Process(es)

response to hypoxia
membrane protein ectodomain proteolysis
calcium ion transport
Notch signaling pathway
Notch receptor processing
protein processing
membrane protein intracellular domain proteolysis
intracellular signal transduction
amyloid precursor protein catabolic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of catalytic activity
ephrin receptor signaling pathway
beta-amyloid metabolic process

Function(s)

endopeptidase activity
aspartic-type endopeptidase activity
protein binding