s56845

Gene Symbol:

AKR1C2 AKR1C1

Gene Name:

aldo-keto reductase family 1, member C2

aldo-keto reductase family 1 member C1

Gene Aliases:

AKR1C-pseudo, BABP, DD, DD-2, DD/BABP, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8, TDD

2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB

Chromosome Location:

Chr.10: 4987775 - 5018033 on Build GRCh38

Chromosome Location:

Chr.10: 4963262 - 4979967 on Build GRCh38

UniGene ID:

Hs.460260

Hs.460260

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: AKR1C2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001354.5	NP_001345.1	6	794
	NM_205845.2	NP_995317.1	5	694
GenBank mRNA	AB021654.1	-	4	381
	AB031084.1	-	4	381
	AB209017.1	-	4	448
	AK091194.1	-	5	2048
	AK290304.1	-	4	437
	BC007024.1	-	4	403	3681970
	BC063574.1	-	5	661	3877666
	BT006653.1	-	4	381
	M33376.1	-	4	336
	S68330.1	-	4	387
	U05598.1	-	4	404

Gene Symbol: AKR1C1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001353.5	NP_001344.2	4	564
GenBank mRNA	AB031083.1	-	4	381
	BC015490.2	-	4	398	3877178
	BC020216.1	-	4	397	4662654
	BC040210.1	-	9	1223	4825338
	BM923712.1	-	4	413
	BT007197.1	-	4	381
	D26124.1	-	4	332
	M86609.1	-	4	387
	S68290.1	-	4	372
	U05684.1	-	4	384

More Information

Panther Classification:

Molecular Function -

oxidoreductase, reductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

prostaglandin metabolic process
G-protein coupled receptor signaling pathway
digestion
steroid metabolic process
positive regulation of cell proliferation
epithelial cell differentiation
progesterone metabolic process
daunorubicin metabolic process
doxorubicin metabolic process
positive regulation of protein kinase B signaling
oxidation-reduction process
cellular response to jasmonic acid stimulus
cellular response to prostaglandin D stimulus
retinoid metabolic process
xenobiotic metabolic process
bile acid metabolic process
bile acid and bile salt transport
intestinal cholesterol absorption
retinal metabolic process
cholesterol homeostasis
response to organophosphorus
protein homooligomerization

Function(s)

alditol:NADP+ 1-oxidoreductase activity
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
phenanthrene 9,10-monooxygenase activity
carboxylic acid binding
bile acid binding
ketosteroid monooxygenase activity
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
aldo-keto reductase (NADP) activity
protein binding
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
androsterone dehydrogenase (B-specific) activity
indanol dehydrogenase activity