s5803 Validated

• Gene Symbol: GCLM
• Gene Name: glutamate-cysteine ligase modifier subunit
• Gene Aliases: GLCLR
• Chromosome Location: Chr.1: 93885199 - 93909598 on Build GRCh38
• UniGene ID: Hs.315562
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GCLM
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001308253.1	NP_001295182.1	6	1130
	NM_002061.3	NP_002052.1	7	1196
	XM_011541261.2	XP_011539563.1	7	997
	XM_017001056.1	XP_016856545.1	8	1398
	XM_017001057.1	XP_016856546.1	7	1332
GenBank mRNA	AB809606.1	-	6	785
	AK290449.1	-	7	1195
	BC041809.1	-	7	997	5311598
	CR541833.1	-	7	761
	L35546.1	-	7	1014

More Information

Matching Taqman Gene Expression Assay:

Hs00157694_m1

Panther Classification:

Molecular Function -

ligase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

sulfur amino acid metabolic process
cysteine metabolic process
glutamate metabolic process
glutathione biosynthetic process
response to oxidative stress
apoptotic mitochondrial changes
positive regulation of glutamate-cysteine ligase activity
response to drug
negative regulation of neuron apoptotic process
regulation of blood vessel size
response to nitrosative stress
regulation of mitochondrial depolarization
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

glutamate-cysteine ligase activity
enzyme regulator activity
glutamate-cysteine ligase catalytic subunit binding
protein heterodimerization activity