s6092 Validated

Gene Symbol:

GRK6 GRK6P1

Gene Name:

G protein-coupled receptor kinase 6

G protein-coupled receptor kinase 6 pseudogene 1

Gene Aliases:

GPRK6

GPRK6L, GPRK6P, GRK6PS

Chromosome Location:

Chr.5: 177426496 - 177442849 on Build GRCh38

Chromosome Location:

Chr.13: 21319027 - 21320826 on Build GRCh38

UniGene ID:

Hs.235116

Hs.719428

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: GRK6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001004105.2	NP_001004105.1	6	659
	NM_001004106.2	NP_001004106.1	6	659
	NM_002082.3	NP_002073.2	6	659
	XM_006714858.3	XP_006714921.1	4	1300
	XM_006714859.2	XP_006714922.1	6	571
	XM_011534537.2	XP_011532839.1	5	411
GenBank mRNA	AF040751.1	-	6	502
	AF040752.1	-	6	502
	AK056697.1	-	4	637
	BC009277.2	-	6	599	4053197
	BC017272.1	-	6	548	4640283
	BU507609.1	-	6	658
	BX382886.2	-	6	657
	L16862.1	-	6	561

Gene Symbol: GRK6P1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK295462.1	-	1	564

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001112713, NM_001112712, NM_031657, XM_006253653, XM_008771504, and others.
This siRNA also targets the following transcripts in Mouse: NM_001038018, NM_001286064, NM_001286063, NM_001286066, NM_001112711, and others.

Matching Taqman Gene Expression Assay:

Hs00357776_g1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

desensitization of G-protein coupled receptor protein signaling pathway
protein phosphorylation
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of anion channel activity
Wnt signaling pathway

Function(s)

G-protein coupled receptor kinase activity
protein binding
ATP binding
beta-adrenergic receptor kinase activity