s63371

• Gene Symbol: Casp1
• Gene Name: caspase 1
• Gene Aliases: ICE, Il1bc
• Chromosome Location: Chr.9: 5298517 - 5307281 on Build GRCm38
• UniGene ID: Mm.1051
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Casp1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009807.2	NP_033937.2	7	1163
GenBank mRNA	AK132826.1	-	5	1875
	BC008152.1	-	7	1163	3583883
	L03799.1	-	6	965
	L28095.1	-	7	1009

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012762, FQ228818, U34621, S79676, D85899, and others.

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

response to hypoxia
microglial cell activation
proteolysis
apoptotic process
myoblast fusion
memory
response to bacterium
regulation of autophagy
response to organic cyclic compound
protein processing
response to lipopolysaccharide
interleukin-1 beta production
response to ATP
response to drug
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of circadian sleep/wake cycle, non-REM sleep
positive regulation of cytokine secretion
positive regulation of interleukin-1 alpha secretion
positive regulation of interleukin-1 beta secretion
regulation of inflammatory response
mitochondrial depolarization
membrane hyperpolarization
pyroptosis
cellular response to organic substance
programmed necrotic cell death
toxin transport

Function(s)

endopeptidase activity
cysteine-type endopeptidase activity
protein binding
peptidase activity
cysteine-type peptidase activity
hydrolase activity
scaffold protein binding