s8630 Validated

• Gene Symbol: MDM2
• Gene Name: MDM2 proto-oncogene
• Gene Aliases: ACTFS, HDMX, hdm2
• Chromosome Location: Chr.12: 68808149 - 68845544 on Build GRCh38
• UniGene ID: Hs.484551
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MDM2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001145337.2	NP_001138809.1	3	198
	NM_001145339.2	NP_001138811.1	3	448
	NM_001145340.2	NP_001138812.1	3	198
	NM_001278462.1	NP_001265391.1	3	198
	NM_002392.5	NP_002383.2	3	448
	XM_005268872.4	XP_005268929.1	3	376
	XM_006719400.3	XP_006719463.1	3	471
GenBank mRNA	AF092843.1	-	3	156
	AF092844.1	-	3	156
	AF092845.1	-	3	156
	AF385322.1	-	2	124
	AF385323.1	-	2	124
	AF385324.1	-	2	124
	AF385326.1	-	2	124
	AF385327.1	-	2	124
	AJ278975.1	-	2	124
	AJ278977.1	-	2	124
	AJ430612.1	-	2	124
	AJ430614.1	-	2	124
	AJ491698.1	-	2	124
	AJ491699.1	-	2	124
	AJ491700.1	-	2	124
	AJ491701.1	-	2	124
	AJ550517.1	-	2	124
	AJ550518.1	-	2	124
	AJ550519.1	-	2	124
	AK290341.1	-	3	398
	AM902642.1	-	2	124
	AM902643.1	-	2	124
	AM902644.1	-	2	124
	AM902646.1	-	2	124
	AM902647.1	-	2	124
	AM902648.1	-	2	124
	AM902649.1	-	2	124
	AM902650.1	-	2	124
	AM902651.1	-	2	124
	AM902654.1	-	2	124
	AM902655.1	-	2	124
	AM902656.1	-	2	124
	AM902657.1	-	2	124
	AM902658.1	-	2	124
	AM902659.1	-	2	124
	AM902660.1	-	2	124
	AM902661.1	-	2	124
	AM902663.1	-	2	124
	AM902664.1	-	2	124
	AM902665.1	-	2	124
	AM902666.1	-	2	124
	AM902667.1	-	2	124
	AM902668.1	-	2	124
	AM902669.1	-	2	124
	AM902672.1	-	2	124
	AM902674.1	-	2	124
	AM902675.1	-	2	124
	AM902676.1	-	2	124
	AM902678.1	-	2	124
	AM902679.1	-	2	124
	AM902680.1	-	2	124
	AM902681.1	-	2	124
	BC152384.1	-	2	127
	BC152390.1	-	2	127
	BE296905.1	-	3	413
	BT007258.1	-	2	124
	EU076746.1	-	3	198
	EU076747.1	-	3	198
	EU076749.1	-	3	198
	HM213901.1	-	2	124
	HM213902.1	-	2	124
	HM213903.1	-	2	124
	HM213904.1	-	2	124
	HY174841.1	-	3	450
JX015379.1	-	2	124
JX015380.1	-	2	124
JX015381.1	-	2	124
JX015382.1	-	2	124
JX015383.1	-	2	124
JX015384.1	-	2	124
JX015385.1	-	2	124
JX015387.1	-	2	124
JX015388.1	-	2	124
JX015389.1	-	2	124
JX015390.1	-	2	124
JX015391.1	-	2	124
JX015392.1	-	2	124
M92424.1	-	3	435
U33201.1	-	2	124
U33203.1	-	2	124
Z12020.1	-	3	435

More Information

Matching Taqman Gene Expression Assay:

Hs00234753_m1

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel development
blood vessel remodeling
regulation of heart rate
atrioventricular valve morphogenesis
endocardial cushion morphogenesis
ventricular septum development
atrial septum development
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
traversing start control point of mitotic cell cycle
positive regulation of cell proliferation
response to toxic substance
response to carbohydrate
response to iron ion
positive regulation of gene expression
negative regulation of protein processing
viral process
protein ubiquitination
protein sumoylation
peptidyl-lysine modification
protein destabilization
response to magnesium ion
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein localization to nucleus
regulation of protein catabolic process
response to cocaine
response to drug
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to morphine
negative regulation of DNA damage response, signal transduction by p53 class mediator
establishment of protein localization
response to ether
negative regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
response to antibiotic
positive regulation of protein export from nucleus
response to steroid hormone
cardiac septum morphogenesis
cellular response to hydrogen peroxide
negative regulation of cell cycle arrest
cellular response to antibiotic
cellular response to vitamin B1
cellular response to alkaloid
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
cellular response to estrogen stimulus
cellular response to hypoxia
cellular response to UV-C
regulation of signal transduction by p53 class mediator
negative regulation of signal transduction by p53 class mediator

Function(s)

p53 binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
SUMO transferase activity
enzyme binding
ubiquitin protein ligase binding
identical protein binding
peroxisome proliferator activated receptor binding
ubiquitin protein ligase activity
scaffold protein binding