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1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%, Thermo Scientific Chemicals
Description
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3'-amino-3'-deoxyadenosine-5'-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.
Solubility
Soluble in acetonitrile dichloromethane, dimethylformamide, and tetrahydrofuran. Slightly soluble in water.
Notes
Sensitive to moisture. Incompatible with strong acids, strong oxidizing agents and moisture.
Specifications
| Melting Point | ∽113°C |
| Linear Formula | CH3CH2N=C=N(CH2)3N(CH3)2·HCl |
| Quantity | 1 g |
| Beilstein | 5764110 |
| Sensitivity | Moisture sensitive |
| Solubility Information | Soluble in acetonitrile dichloromethane,dimethylformamide,and tetrahydrofuran. Slightly soluble in water. |
| Formula Weight | 191.7 |
| Percent Purity | ≥98% |
| Chemical Name or Material | 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride |
Safety and Handling
| Hazard Category | H302-H315-H317-H319 |
| Hazard Statement | GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. |
| Precautionary Statement | P261-P264b-P270-P272-P280-P301+P312-P302+P352-P305+P351+P338-P330-P333+P313-P362-P501c |
| DOTInformation | Hazard Class: 9; Packaging Group: III |
| EINECSNumber | 247-361-2 |
| RTECSNumber | FF2200000 |
| TSCA | Yes |
| Recommended Storage | Keep cold |
RUO – Research Use Only
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