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Thermo Scientific™ Lab Vision™ α -1-Antitrypsin Ab-1, Rabbit Polyclonal Antibody

Obtain accurate, reproducible results with Thermo Scientific™ α-1-Antitrypsin Ab-1, Rabbit Polyclonal Antibody.

$265.00 - $684.50

Specifications

Antigen alpha-1-Antitrypsin Ab-1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
Host Species Rabbit
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Products 4
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
RB367A
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Thermo Scientific™
RB367A
1mL
Each for $684.50
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RB367A1
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Thermo Scientific™
RB367A1
500μL
Each for $457.00
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RB367R7
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Thermo Scientific™
RB367R7
7mL
Each for $265.00
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RB367R1
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Thermo Scientific™
RB367R1
1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
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Description

Description

Obtain accurate, reproducible results with Thermo Scientific™ α-1-Antitrypsin Ab-1, Rabbit Polyclonal Antibody. This antibody detects alpha-1-antitrypsin (alpha-1-AT), which exists in a number of genetic variants of which MM variant is the most common.

Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma. Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn. Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation. Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Baboon, Monkey, Horse and Mink. Does not react with cow, kangaroo, pig, goat, sheep, cat, dog, guinea pig, mouse and chicken. Others not known.

Immunogen: Purified human serum α-1-AT

Positive Control: Tonsil

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO

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Specifications

Specifications

alpha-1-Antitrypsin Ab-1
Polyclonal
Rabbit
Enzyme
Purified human serum alpha-1-AT
Immunohistochemistry (Paraffin)
Unconjugated
RUO
Primary
IgG
SDS
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