Alfa Aesar 2,2,2-Trifluoroethanol, 99+%
Manufacturer: Alfa Aesar A1078818
Trifluoroethanol serves as a solvent and a raw material in organic chemistry and biology. TFE is a solvent of choice for hydrogen peroxide-mediated oxidations of sulfides. Trifluoroethanol acts as a protein denaturant. It is used in the manufacture of certain pharmaceuticals and drug substances. The drug fluromer, which is 2,2,2-trifluoro-1-vinyloxyethane, is the vinyl ether of trifluorethanol. It is an effective solvent for peptides and proteins, and used for NMR-based protein folding studies, and in the manufacture of nylon. As a source of the trifluoromethyl group, it is employed in several organic reactions, for example in Still-Gennari modification of Horner-Wadsworth-Emmons reaction (HWE) reaction.
Miscible with water, ethers, ketones, alcohols and chloroform.
|74° to 75°C|
Safety and Handling
SDS & Safety Documents
GHS H Statement
Toxic if swallowed.
Toxic in contact with skin.
Causes serious eye damage.
Flammable liquid and vapor.
Harmful if inhaled.
Causes skin irritation.
May cause respiratory irritation.
GHS P Statement
Keep away from heat/sparks/open flames/hot surfaces.
- No smoking.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Remove/Take off immediately all contaminated clothing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
DOTInformation : Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, TOXIC, N.O.S.
RTECSNumber : KM5250000
TSCA : TSCA
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