Tocris™ 2,3-DCPE hydrochloride

Selectively induces cancer cell apoptosis

Manufacturer: Tocris™ 2137/50

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Catalog No. 21-375-0

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For Research Use Only


    Specifications

    Product Type 2,3-DCPE hydrochloride
    Inhibitors 2,3-DCPE hydrochloride
    Purity >99
    Molecular Weight 300.61
    Quantity 50mg

    Selectively induces apoptosis and downregulates Bcl-XL protein expression in various human cancer cells versus normal cells in vitro. IC50 values are 0.89 and 12.6µM for LoVo human colon cancer cell line and normal human fibroblasts respectively. Induces p21 expression and S-phase arrest in cancer cells via ERK-mediated pathways.

    • Chemical Name: 2-[[3-(2,3-Dichlorophenoxy)propyl]amino]ethanol hydrochloride
    • Formula: C11H15Cl2NO2.HCl
    • CAS Number: 1009555-55-8
    • Solubility: Soluble to 100mM in water
    • Purity: >99

  • Description & Specifications

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