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  6. 2-Methoxyestradiol, Tocris Bioscience™

2-Methoxyestradiol, Tocris Bioscience™

Catalog Number p-4783686
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
362-07-2
C19H26O3
302.414
CQOQDQWUFQDJMK-SSTWWWIQSA-N
2-methoxyestradiol, panzem, 2-methoxyestradiol-17beta, 2-hydroxyestradol 2-methyl ether, estradiol, 2-methoxy, 2-hydroxyestradiol 2-methyl ether, pulmolar, 2-methoxyestra-1,3,5 10-triene-3,17beta-diol, panzem ncd, 2-methoxy-17beta-estradiol
66414
CHEBI:28955
(8R,9S,13S,14S,17S)-2-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)OC)O
This item is not returnable. View return policy
362-07-2
C19H26O3
302.414
CQOQDQWUFQDJMK-SSTWWWIQSA-N
2-methoxyestradiol, panzem, 2-methoxyestradiol-17beta, 2-hydroxyestradol 2-methyl ether, estradiol, 2-methoxy, 2-hydroxyestradiol 2-methyl ether, pulmolar, 2-methoxyestra-1,3,5 10-triene-3,17beta-diol, panzem ncd, 2-methoxy-17beta-estradiol
66414
CHEBI:28955
(8R,9S,13S,14S,17S)-2-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)OC)O

Description

Apoptotic and antiangiogenic agent

Apoptotic, antiproliferative and antiangiogenic agent, in vitro and in vivo; acts via an estrogen receptor-independent mechanism. Induces p53-induced apoptosis via two pathways: activation of p38 and NF-κB; and activation of JNK and AP-1 leading to Bcl-2 phosphorylation. Also upregulates death receptor 5 and binds to tubulin, inhibiting its assembly.
Quantity 10 mg
Formula Weight 302.41
Percent Purity >99%
Chemical Name or Material 2-Methoxyestradiol

Safety and Handling

Recommended Storage Store at Room Temperature
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