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Alfa Aesar™ 3,3',5-Triiodo-L-thyronine, 95%

Manufacturer:  Alfa Aesar™ H3406806

Quantity 5g

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Catalog No. AAH3406806


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Specifications

Description

Applications
Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3 ft., 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3 ft., 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and was shown to be saturable, reversible, and stereospecific. A fluorescent derivative of the thyroid hormone 3,3 ft.-triiodo-L-thyronine binds to cultured mouse fibroblasts; such binding is saturable. 3,3 ft.,5-Triiodo-L-thyronine Up-regulation of Na,K-ATPase Activity and Cell Surface Expression in Alveolar Epithelial Cells Is Src Kinase- and Phosphoinositide 3-Kinase-dependent.

Solubility
Insoluble in water, ethanol and propylene glycol. Soluble in dilute alkalies.

Notes
Light Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, Strong bases, light.
Description & Specifications

Chemical Identifiers

6893-02-3
650.97
O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine; Liothyronine
C15H12I3NO4
MFCD00002593
3,3',5-Triiodo-L-thyronine

Specifications

+25° (c=1 in 1M HCl/Ethanol 1:2)
5g
C15H12I3NO4
MFCD00002593
3,3',5-Triiodo-L-thyronine
234° to 238°C
6893-02-3
650.97
O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine; Liothyronine
95%

Safety and Handling

SDS & Safety Documents

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : AY6750000

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