Alfa Aesar™ 3,3',5-Triiodo-L-thyronine, 95%

Manufacturer: Alfa Aesar™ H3406806

Quantity 5g

 View more versions of this product

Catalog No. AAH3406806

  Check Availability
Add to Cart

    Chemical Identifiers

    CAS 6893-02-3
    Molecular Formula C15H12I3NO4
    Formula Weight 650.97g/mol
    MDL Number MFCD00002593
    Synonym O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine; Liothyronine
    Chemical Name or Material 3,3',5-Triiodo-L-thyronine

    Specifications

    Melting Point 234° to 238°C
    Quantity 5g
    Optical Rotation +25° (c=1 in 1M HCl/Ethanol 1:2)
    CAS 6893-02-3
    Molecular Formula C15H12I3NO4
    Formula Weight 650.97g/mol
    MDL Number MFCD00002593
    Synonym O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine; Liothyronine
    Health Hazard 1 Warning
    Health Hazard 2 GHS H Statement
    H315-H319-H335
    Causes skin irritation.
    Causes serious eye irritation.
    May cause respiratory irritation.
    Health Hazard 3 GHS P Statement
    P261-P280-P305+P351+P338-P304+P340-P405-P501a
    Avoid breathing dust/fume/gas/mist/vapors/spray.
    Wear protective gloves/protective clothing/eye protection/face protection.
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
    IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.
    RTECS Number AY6750000
    Chemical Name or Material 3,3',5-Triiodo-L-thyronine
    Assay 95%

    Description

    Applications
    Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3 ft., 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3 ft., 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and was shown to be saturable, reversible, and stereospecific. A fluorescent derivative of the thyroid hormone 3,3 ft.-triiodo-L-thyronine binds to cultured mouse fibroblasts; such binding is saturable. 3,3 ft.,5-Triiodo-L-thyronine Up-regulation of Na,K-ATPase Activity and Cell Surface Expression in Alveolar Epithelial Cells Is Src Kinase- and Phosphoinositide 3-Kinase-dependent.

    Solubility
    Insoluble in water, ethanol and propylene glycol. Soluble in dilute alkalies.

    Notes
    Light Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, Strong bases, light.

    GHS H Statement
    H315-H319-H335
    Causes skin irritation.
    Causes serious eye irritation.
    May cause respiratory irritation.

    GHS P Statement
    P261-P280-P305+P351+P338-P304+P340-P405-P501a
    Avoid breathing dust/fume/gas/mist/vapors/spray.
    Wear protective gloves/protective clothing/eye protection/face protection.
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
    IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.

    Warning

    SDS & Safety Documents

  • Description & Specifications
  • Safety and Handling

Related Products


Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit