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3-Methylcytosine Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA540098

Catalog No. PA540098


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Description

Description

3-methylcytosine arises by erroneous methylation of DNA through spontaneous exposure to endogenous S-adenosyl methionine (SAM). Since the N3-position in cytosine is protected in double stranded DNA, this phenomenon mainly occurs in single stranded DNA. The resulting 3-mC is toxic and mutagenic and increased levels of 3-mC seem to impair cell proliferation. Therefore, it has to be repaired by the cell. This is established by oxidative demethylation, which is catalyzed by the AlkB protein.
Specifications

Specifications

3-Methylcytosine
Polyclonal
Unconjugated
Liquid
Rabbit
IgG
50 μg
-20°C or -80°C if preferred
Primary
Human, Mouse
Peptide Array
1.8 mg/mL
PBS with 0.05% Proclin 300, 0.05% sodium azide; pH 7.4
3mc; 3-mC; 3-meC; C5H7NO3; 3-Methyl-cytosine
Human BSA-conjugated 3-methylcytosine (3-mC).
Protein G
RUO
Antibody
Polyclonal
Documents
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