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3-Methylcytosine (3-mC) Rabbit anti-Human, Mouse, Unconjugated, Polyclonal, Active Motif™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

$135.30 - $534.00

Specifications

Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Antigen 3-Methylcytosine (3-mC)
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-4144 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
61180
10 μL
Each for $135.30
Add to cart
 
50-199-4143 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
61179
100 μL
Each for $534.00
Add to cart
 
Description

Description

3-methylcytosine arises by erroneous methylation of DNA through spontaneous exposure to endogenous S-adenosyl methionine (SAM). Since the N3-position in cytosine is protected in double stranded DNA, this phenomenon mainly occurs in single stranded DNA. The resulting 3-mC is toxic and mutagenic and increased levels of 3-mC seem to impair cell proliferation. Therefore, it has to be repaired by the cell. This is established by oxidative demethylation, which is catalyzed by the AlkB protein.
Specifications

Specifications

Polyclonal
Primary
3-Methylcytosine (3-mC)
Unconjugated
SDS
Product Certifications
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