Alfa Aesar™ 3-Phenylpropionyl chloride, 98%

Manufacturer: Alfa Aesar™ A1086030

Quantity 250g

 View more versions of this product

Catalog No. AAA1086030

  Check Availability
Add to Cart

    Chemical Identifiers

    CAS 645-45-4
    Molecular Formula C6H5(CH2)2COCl
    Formula Weight 168.62g/mol
    MDL Number MFCD00000748
    UN Number UN3265
    Beilstein 742586
    Synonym Hydrocinnamoyl chloride
    Chemical Name or Material 3-Phenylpropionyl chloride

    Specifications

    Odor Acrid
    Boiling Point 225°C
    Melting Point −7°C
    Flash Point 108°C (226°F)
    Quantity 250g
    CAS 645-45-4
    Molecular Formula C6H5(CH2)2COCl
    Formula Weight 168.62g/mol
    MDL Number MFCD00000748
    UN Number UN3265
    Beilstein 742586
    Synonym Hydrocinnamoyl chloride
    Health Hazard 1 Danger
    Health Hazard 2 GHS H Statement
    H314-H318-H332
    Causes severe skin burns and eye damage.
    Causes serious eye damage.
    Harmful if inhaled.
    Health Hazard 3 GHS P Statement
    P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
    Do not breathe dust/fume/gas/mist/vapors/spray.
    IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
    Continue rinsing.
    IF SWALLOWED: Rinse mouth.
    Do NOT induce vomiting.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.
    DOT Information Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
    RTECS Number MW5652395
    TSCA TSCA
    Chemical Name or Material 3-Phenylpropionyl chloride
    Assay 98%

    Description

    Applications
    The 3-phenylpropionate (dihydrocinnamoyl) ester has been used as a protecting group in nucleoside synthesis. Used in the synthesis of 1-Phenyl-3-methyl-4-acyl-5- pyrazolones. N-(3-phenyl-n-propyl)-1-phenyl-2-aminopropane were prepared by acylation of the appropriate amine with 3-phenylpropionyl chloride followed by reduction of the resulting amide with either LiA1H4. For the preparation of the phenylacetyl (PA) and 3-phenylpropionyl (PP) derivatives, the corresponding amino acids were coupled in the usual manner with phenylacetyl chloride or 3-phenylpropionyl chloride in the presence of either NaOH(PA-LD- and DL-Pgly. 3-Phenylpropionyl chloride (4) was treated with diazomethane to give diazoketone. Allyloxy resin 12 was acylated with 3-phenylpropionyl chloride and treated with 50% TFA for 1 h followed by treatment with Pd(PPh3)4/PPh3 in solution to furnish the desired hydrox- amic acid.

    Notes
    Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, amines, alcohols, active metals, bases, water, moisture.

    GHS H Statement
    H314-H318-H332
    Causes severe skin burns and eye damage.
    Causes serious eye damage.
    Harmful if inhaled.

    GHS P Statement
    P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
    Do not breathe dust/fume/gas/mist/vapors/spray.
    IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
    Continue rinsing.
    IF SWALLOWED: Rinse mouth.
    Do NOT induce vomiting.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.

    Danger

    SDS & Safety Documents

  • Description & Specifications
  • Safety and Handling

Related Products


Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit